Cetylev

Acute ingestion: assess history and timing of acetaminophen ingestion and obtain serum acetaminophen level at least 4hrs post-ingestion. If time of ingestion is unknown: give loading dose immediately and obtain acetaminophen level to determine need for continued treatment. If serum acetaminophen level unobtainable within 8hr interval or if toxicity evident: give loading dose immediately then continue for a total of 17 doses. If >8hrs post-ingestion and time of ingestion is known, give loading dose immediately and obtain acetaminophen level to determine need for continued treatment. If <8hrs post-ingestion and time of ingestion and the acetaminophen level are known, plot level on Rumack-Matthew nomogram to determine whether or not to initiate treatment (see full labeling). Loading dose: 140mg/kg. Maintenance dose: 70mg/kg every 4hrs for a total of 17 doses. May be administered by nasoduodenal tube or can consider IV form if unable to retain Cetylev. For weight-based dosage and others: see full labeling. RSI: obtain acetaminophen level and other lab tests for guidance; or, contact regional poison center.