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Excedrin Extra Strength Generic Name & Formulations
Legal Class
OTC
General Description
Acetaminophen 250mg, aspirin 250mg, caffeine 65mg; caplets.
Pharmacological Class
Analgesic + salicylate.
How Supplied
Caplets—24, 200
Manufacturer
Excedrin Extra Strength Indications
Indications
Minor aches and pains.
Excedrin Extra Strength Dosage and Administration
Adult
Take with full glass of water. 2 caplets every 6 hours as needed; max 8 caplets/day.
Children
Not recommended.
Excedrin Extra Strength Contraindications
Contraindications
NSAID allergy. Varicella, vaccinia in children and teenagers. 3rd trimester of pregnancy.
Excedrin Extra Strength Boxed Warnings
Not Applicable
Excedrin Extra Strength Warnings/Precautions
Warnings/Precautions
Reye's syndrome. Persistent or unresponsive headache. Hypertension. Cardiovascular disease. Asthma. Peptic ulcer. GI bleeding disorders. Liver cirrhosis. Hepatic or renal impairment. Discontinue if signs/symptoms of GI bleed, tinnitus, loss of hearing, or new symptoms occur. Reevaluate if pain worsens or persists for >10 days or if fever worsens or persists for >3 days. Elderly (≥60yrs). Pregnancy. Nursing mothers.
Excedrin Extra Strength Pharmacokinetics
See Literature
Excedrin Extra Strength Interactions
Interactions
May potentiate anticoagulants, hypoglycemics, methotrexate. May antagonize uricosurics. Increased risk of liver toxicity and/or GI bleed with ≥3 alcoholic drinks/day or concomitant other drugs containing acetaminophen, NSAIDs. Caution with diuretics, corticosteroids.
Excedrin Extra Strength Adverse Reactions
Adverse Reactions
Gastric upset, prolonged bleeding time, urticaria, anaphylaxis; overdosage: salicylism, hepatoxicity.
Excedrin Extra Strength Clinical Trials
See Literature
Excedrin Extra Strength Note
Not Applicable
Excedrin Extra Strength Patient Counseling
See Literature
