Tymlos

Avoid in those with increased baseline risk for osteosarcoma (eg, open epiphyses, metabolic bone disease, Paget's disease of the bone, bone metastases, history of skeletal malignancies, prior external beam or skeletal implant radiation therapy, hereditary disorders predisposing to osteosarcoma), pre-existing hypercalcemia or underlying hypercalcemic disorder (eg, primary hyperparathyroidism). Urolithiasis. Hypercalciuria. Severe renal impairment: monitor. Pregnancy, nursing mothers: not indicated.