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Aczone 7.5% Generic Name & Formulations
Legal Class
Rx
General Description
Dapsone 7.5%; gel.
Pharmacological Class
Sulfone.
See Also
How Supplied
Gel 5% (tubes)—30g, 60g, 90g; Gel 7.5% (pumps)—30g, 60g, 90g
Manufacturer
Generic Availability
NO
Aczone 7.5% Indications
Indications
Acne vulgaris.
Aczone 7.5% Dosage and Administration
Adults and Children
<9yrs: not established. Wash skin and pat dry. ≥9yrs: apply pea-sized amount to entire face or other affected area in a thin layer once daily. Rub in gently and completely. Wash hands after use. Reevaluate if no improvement after 12 weeks.
Aczone 7.5% Contraindications
Not Applicable
Aczone 7.5% Boxed Warnings
Not Applicable
Aczone 7.5% Warnings/Precautions
Warnings/Precautions
Avoid in congenital or idiopathic methemoglobinemia. G6PD deficiency: may have increased risk of methemoglobinemia or hemolytic anemia; discontinue if occurs. Pregnancy. Nursing mothers.
Aczone 7.5% Pharmacokinetics
See Literature
Aczone 7.5% Interactions
Interactions
Increased risk of hemolysis in G6PD-deficient patients with concomitant trimethoprim/sulfamethoxazole, other folic acid antagonists (eg, pyrimethamine), anticonvulsants, rifampin, St. John's wort. Increased risk of methemoglobinemia with concomitant sulfonamides, acetaminophen, chloroquine, nitrates, nitrites, nitrofurantoin, phenobarbital, phenytoin, primaquine, quinine, and others. Skin/hair discoloration with topical benzoyl peroxide.
Aczone 7.5% Adverse Reactions
Adverse Reactions
Application site reactions (oiliness, peeling, dryness, erythema, pruritus).
Aczone 7.5% Clinical Trials
See Literature
Aczone 7.5% Note
Not Applicable
Aczone 7.5% Patient Counseling
See Literature
