Acuvail

— THERAPEUTIC CATEGORIES —
  • Ocular allergy/inflammation

Acuvail Generic Name & Formulations

General Description

Ketorolac tromethamine 0.45%; oph soln; preservative-free.

Pharmacological Class

NSAID.

How Supplied

Single-use vials (0.4mL)—30

Manufacturer

Acuvail Indications

Indications

Ocular pain and inflammation after cataract surgery.

Acuvail Dosage and Administration

Adult

1 drop in the affected eye twice daily beginning 1 day prior to surgery, continue on day of surgery and through first 2 weeks post-op. Concomitant other topical ophthalmics (eg, alpha-agonists, beta-blockers, carbonic anhydrase inhibitors, cycloplegics, mydriatics): administer at least 5 minutes apart.

Children

Not established.

Acuvail Contraindications

Not Applicable

Acuvail Boxed Warnings

Not Applicable

Acuvail Warnings/Precautions

Warnings/Precautions

Do not administer while wearing contacts. Aspirin/NSAID sensitivity. Asthma. Bleeding tendencies. Complicated or repeated ocular surgeries. Corneal defects/denervation. Ocular surface diseases. Diabetes. Rheumatoid arthritis. May delay wound healing. Monitor cornea; discontinue if corneal epithelial breakdown occurs. Pregnancy (Cat.C): avoid in late pregnancy. Nursing mothers.

Acuvail Pharmacokinetics

Metabolism

Hepatic. >99% serum protein bound.

Elimination

Renal.

Acuvail Interactions

Interactions

Concomitant topical steroids may increase potential for healing problems.

Acuvail Adverse Reactions

Adverse Reactions

Increased intraocular pressure, conjunctival hyperemia and/or hemorrhage, corneal edema, ocular pain, headache, tearing, blurred vision; keratitis, increased ocular bleeding (including hyphemas).

Acuvail Clinical Trials

See Literature

Acuvail Note

Not Applicable

Acuvail Patient Counseling

See Literature