Muscle spasms Archives - MPR

AMRIX

Haymarket Media — Thu, 22 Jul 2021 10:45:59 +0000

Cyclobenzaprine HCl 15mg, 30mg; ext-rel caps.

Baclofen

Haymarket Media — Tue, 30 Aug 2022 18:57:45 +0000

Baclofen 5mg, 10mg+, 20mg+; tabs; +scored.

BOTOX

Haymarket Media — Wed, 06 Sep 2023 20:33:23 +0000

OnabotulinumtoxinA 100 Units, 200 Units; per vial; vacuum-dried pwd for IM, intradermal, or intradetrusor inj after reconstitution and dilution; contains human albumin; preservative-free.

Cyclobenzaprine HCl Tablets

Haymarket Media — Wed, 09 Aug 2023 15:54:53 +0000

Cyclobenzaprine HCl 5mg, 7.5mg, 10mg; tabs.

DANTRIUM

Haymarket Media — Thu, 22 Jul 2021 10:46:34 +0000

Dantrolene sodium 25mg, 50mg, 100mg; caps.

DAXXIFY

Haymarket Media — Thu, 17 Aug 2023 14:33:32 +0000

DaxibotulinumtoxinA-lanm 50 Units, 100 Units; per vial; lyophilizied pwd for IM inj after reconstitution; preservative-free.

Diazepam Injection

Haymarket Media — Fri, 17 Feb 2023 19:51:34 +0000

Diazepam 5mg/mL; soln for IM or IV use; contains propylene glycol 40%, ethyl and benzyl alcohol.

Diazepam Intensol

Haymarket Media — Thu, 23 Feb 2023 20:18:23 +0000

Diazepam 5mg; per 1mL; concentrated soln; contains alcohol 19%.

Diazepam Oral Solution

Haymarket Media — Thu, 23 Feb 2023 20:18:06 +0000

Diazepam 5mg; per 5mL; wintergreen-spice flavor.

DYSPORT

Haymarket Media — Wed, 04 Oct 2023 18:04:26 +0000

AbobotulinumtoxinA 300 Units, 500 Units; per vial; lyophilized pwd for IM inj after reconstitution; contains human albumin, lactose. May contain cow's milk proteins (trace amounts).

FLEQSUVY

Haymarket Media — Thu, 31 Mar 2022 12:39:33 +0000

Baclofen 5mg/mL; oral susp; grape-flavor.

GABLOFEN

Haymarket Media — Thu, 22 Jul 2021 11:15:17 +0000

Baclofen 50mcg/mL, 500mcg/mL, 1000mcg/mL, 2000mcg/mL; for intrathecal inj; preservative-free.

LIORESAL INTRATHECAL

Haymarket Media — Thu, 22 Jul 2021 11:30:52 +0000

Baclofen 50mcg/mL, 500mcg/mL, 2000mcg/mL; for intrathecal inj; preservative-free.

LYVISPAH

Haymarket Media — Wed, 01 Jun 2022 13:27:31 +0000

Baclofen 5mg, 10mg, 20mg; oral granules; strawberry-flavor.

Muscle Spasm Treatments

Haymarket Media — Tue, 21 Oct 2014 22:30:00 +0000

Muscle Spasm Treatments

MUSCLE SPASM TREATMENTS
Generic	Brand		Strength	Form	Usual Adult Dose
Alpha₂-ADRENERGIC AGONIST
tizanidine HCl	Zanaflex	℞	4mg	scored tabs	Usually 4mg, may increase by 2−4mg as needed every 6−8hrs to a max of 3 doses in 24hrs; max 12mg/dose and 36mg/day. Renal impairment (CrCl <25mL/min): Reduce dose. May sprinkle contents of capsules on applesauce (may affect absorption). Tabs and caps not bioequivalent under fed conditions.
tizanidine HCl	Zanaflex	℞	2mg, 4mg, 6mg	caps
ANTICHOLINERGIC MUSCLE RELAXANT (CENTRAL)
orphenadrine citrate	—	℞	100mg	sust-rel tabs	100mg twice daily in AM and PM
orphenadrine citrate	—	℞	60mg/2mL	inj¹	60mg IM or IV every 12hrs
BENZODIAZEPINE
diazepam	—	CIV	5mg/5mL	soln	2−10mg 3−4 times daily. Elderly, debilitated: Initially 2−2.5mg 1−2 times daily; increase gradually.
	—	CIV	5mg/mL	inj⁴	Initially 5−10mg slow IV (5mg/min) or IM. May repeat after 3−4hrs. Tetanus: May need larger dose. Do not use small vein.
	Diazepam Intensol	CIV	5mg/mL	concen– trated soln²	2−10mg 3−4 times daily Elderly, debilitated: Initially 2−2.5mg 1−2 times daily; increase gradually. Mix with liquid or semi-solid food.
	Valium	CIV	2mg, 5mg, 10mg	scored tabs	2−10mg 3−4 times daily Elderly, debilitated: Initially 2−2.5mg 1−2 times daily; increase gradually.
MUSCLE RELAXANT (CENTRAL)
baclofen	—	℞	5mg, 10mg+, 20mg+	tabs (+scored)	5mg 3 times daily; increase in increments of 5mg 3 times daily every 3 days if needed; max 80mg daily
	Gablofen	℞	50mcg/mL, 500mcg/ mL, 1000mcg/ mL, 2000mcg/ mL	intra– thecal inj	Give test dose 1st by intrathecal inj via spinal catheter or lumbar puncture (use 50mcg/mL syringe). Dose titration: see full labeling. Maintenance: titrate individually; maintain some degree of muscle tone. Spinal cord origin: usually 300–800mcg/day. Cerebral origin: usually 90–703mcg/day.
	Lioresal	℞	50mcg/mL, 500mcg/ mL, 2000mcg/ mL	intra– thecal inj
	Lyvispah	℞	5mg, 10mg, 20mg	oral granules	≥12yrs: Initially 5mg 3 times daily for 3 days. May increase by increments of 5mg 3 times daily every 3 days, as needed; up to max 80mg/day. Can be dissolved in the mouth, swallowed, or mixed with up to 15mL of liquid or soft foods.
carisoprodol	Soma	CIV	350mg	tabs	≥16yrs: 250−350mg 3 times daily and at bedtime; max 2−3wks <16yrs: Not established.
carisoprodol	Soma 250	CIV	250mg	tabs
chlorzox– azone	—	℞	375mg, 500mg+, 750mg+	tabs (+scored)	250–500mg 3–4 times daily. Painful musculoskeletal conditions: initially 500mg 3–4 times daily. May increase to 750mg 3–4 times daily if inadequate response. May reduce dose based on improvement.
cyclobenza– prine HCl	—	℞	5mg, 10mg, 7.5mg	tabs	≥15yrs: Initially 5mg 3 times daily; may increase to 10mg 3 times daily; max 2−3wks. Elderly or hepatic impairment: Initially 5mg, then titrate up. <15yrs: Not established.
cyclobenza– prine HCl	Amrix	℞	15mg, 30mg	ext-rel caps	15mg once daily; may increase to 30mg once daily; max 2−3wks. Take at same time each day. Elderly or hepatic impairment: Not recommended.
metaxalone	Skelaxin	℞	800mg	scored tabs	800mg 3−4 times daily.
methocar– bamol	—	℞	500mg	tabs	≥16yrs: Initially 1.5g 4 times daily for 2−3 days; if severe, may give up to 8g/day Maintenance: 1g 4 times daily <16yrs: Not established.
methocar– bamol	—	℞	750mg	tabs	≥16yrs: Initially 1.5g 4 times daily for 2−3 days; if severe, may give up to 8g/day. Maintenance: 750mg every 4hrs or 1.5g 3 times daily. <16yrs: Not established.
MUSCLE RELAXANT (LOCAL)
dantrolene sodium	Dantrium	℞	25mg, 50mg, 100mg	caps	25mg once daily for 7 days, then 25mg 3 times daily for 7 days, then 50mg 3 times daily for 7 days, then 100mg 3 times daily; max 100mg 4 times daily
MUSCLE RELAXANT (CENTRAL) + SALICYLATE
carisoprodol	—	℞	200mg	tabs	1−2 tabs 4 times daily
aspirin	—	℞	325mg	tabs	1−2 tabs 4 times daily
MUSCLE RELAXANT (CENTRAL) + SALICYLATE + OPIOID
carisoprodol	—	CIII	200mg	tabs¹	1−2 tabs 4 times daily
aspirin			325mg
codeine phosphate			16mg
NEUROMUSCULAR BLOCKERS
abobotuli– numtoxin A	Dysport	℞	300 U/vial, 500 U/vial	IM inj³	Spasticity: usual range: 500–1000 Units (upper limb) or 1000–1500 Units (lower limb) divided among selected muscles per treatment session; max 1mL/site. Total max 1500 Units for upper and lower limb combined. May repeat treatment after effect of the previous inj diminishes, but no sooner than 12wks.
incobotuli– numtoxin A	Xeomin	℞	50 U/vial, 100 U/vial, 200 U/vial	IM inj³	See full labeling. Upper limb spasticity (not previously treated): initially give dose at the low end of dosing range and titrate as needed. Max cumulative dose: 400 Units in a treatment session. May repeat treatments no sooner than every 12wks.
onabotuli– numtoxin A	Botox	℞	50 U/vial, 100 U/vial, 200 U/vial	IM inj³	Upper limb spasticity: usual range: 75–400 Units divided among selected muscles per treatment session; max 50 Units/site. Lower limb spasticity: 300–400 Units divided among 5 muscles; max 50 Units/site. May repeat treatment after effect of the previous inj diminishes, but no sooner than 12wks.
NOTES
¹contains sulfites; ²contains alcohol 19%; ³contains human albumin; ⁴contains propylene glycol 40%, ethyl and benzyl alcohol Not an inclusive list of medications and/or doses. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. (Rev. 10/2022)

MYOBLOC

Haymarket Media — Thu, 22 Jul 2021 11:13:13 +0000

RimabotulinumtoxinB 2500 Units/0.5mL, 5000 Units/1mL, 10000 Units/2mL; soln for IM or intraglandular inj; contains human albumin; preservative-free.

VALIUM

Haymarket Media — Fri, 17 Feb 2023 19:52:49 +0000

Diazepam 2mg, 5mg, 10mg; scored tabs.

XEOMIN

Haymarket Media — Fri, 13 Oct 2023 12:47:12 +0000

IncobotulinumtoxinA 50 Units, 100 Units, 200 Units; per vial; lyophilized pwd for IM or intra-salivary gland inj after reconstitution; contains human albumin, sucrose; preservative-free.

ZANAFLEX CAPSULES

Haymarket Media — Thu, 22 Jul 2021 10:48:19 +0000

Tizanidine HCl 2mg, 4mg, 6mg; caps.

ZANAFLEX TABLETS

Haymarket Media — Thu, 22 Jul 2021 10:48:20 +0000

Tizanidine HCl 4mg (quadrisecting score); tabs.