Vaginal Infection Treatments

VAGINAL INFECTION TREATMENTS
Generic	Brand		Form	Adult Dosing
VULVOVAGINAL CANDIDIASIS
butocon– azole	Gynazole‑1	Rx	2% vaginal crm	1 applicatorful once
clotrim– azole	—	OTC	1%, 2% vaginal crm	1 applicatorful at bedtime for 3 nights (2% crm) or 7 nights (1% crm)
flucon– azole	Diflucan	Rx	150mg oral tab	150mg once
ibrexa– fungerp	Brexafemme	Rx	150mg oral tab	VVC: 300mg every 12hrs for 1 day. RVVC: 300mg every 12hrs for 1 day, for a total daily dose of 600mg monthly for 6mos
micon– azole	Monistat 1 Combination Pack	OTC	1200mg vaginal insert + 2% external topical crm	1 insert once (AM or PM); apply external topical crm twice daily as needed for up to 7 days
	Monistat 3 Cream	OTC	4% vaginal crm	1 applicatorful daily at bedtime for 3 nights
	Monistat 3 Combination Pack	OTC	200mg vaginal supp + 2% external topical crm	1 supp, 1 insert, or 1 applicatorful (4% crm) daily at bedtime for 3 nights; apply external topical crm twice daily as needed for up to 7 days
	Monistat 3 Cream Combination Pack	OTC	4% vaginal crm + 2% external topical crm
	Monistat 3 Insert Combination Pack	OTC	200mg vaginal insert + 2% external topical crm
	Monistat 7 Cream	OTC	2% vaginal crm	1 applicatorful daily at bedtime for 7 nights
	Monistat 7 Cream Combination Pack	OTC	2% vaginal crm + 2% external topical crm	1 applicatorful daily at bedtime for 7 nights; apply external topical crm twice daily as needed for up to 7 days
otesecon– azole	Vivjoa*	Rx	150mg oral cap	Vivjoa-only regimen: 600mg (as a single dose) on Day 1; then 450mg (as a single dose) on Day 2; and then 150mg once weekly (every 7 days) starting on Day 14 for 11wks (Weeks 2 through 12). Fluconazole + Vivjoa regimen: oral fluconazole 150mg once on Days 1, 4, and 7; then Vivjoa 150mg once daily for 7 days on Days 14 through 20; and then Vivjoa 150mg once weekly starting on Day 28 for 11wks (Weeks 4 through 14)
tercon– azole	—	Rx	0.8% vaginal crm	1 applicatorful or supp at bedtime for 3 nights
			80mg vaginal supp	1 applicatorful or supp at bedtime for 3 nights
			0.4% vaginal crm	1 applicatorful at bedtime for 7 nights
tiocon– azole	—	OTC	6.5% vaginal oint	1 applicatorful once at bedtime
tiocon– azole	Monistat 1 Vaginal Ointment	OTC	6.5% vaginal oint	1 applicatorful once at bedtime
BACTERIAL VAGINOSIS
clinda– mycin	Cleocin Vaginal Cream	Rx	2% vaginal crm	1 applicatorful for 3−7 nights; in 2nd or 3rd trimester of pregnancy use for 7 nights
	Cleocin Vaginal Ovules	Rx	100mg vaginal supp	1 supp for 3 nights
	Clindesse	Rx	2% vaginal crm	1 applicatorful once
	Xaciato	Rx	2% vaginal gel	1 applicatorful once at any time of the day
metronid– azole	MetroGel Vaginal	Rx	0.75% vaginal gel	1 applicatorful once or twice daily for 5 days
	Nuvessa	Rx	1.3% vaginal gel	1 applicatorful once at bedtime
	Vandazole	Rx	0.75% vaginal gel	1 applicatorful once daily at bedtime for 5 days
secni– dazole	Solosec^†	Rx	2g/pkt oral granules	2g once
tinid– azole	Tindamax	Rx	500mg oral tab	2g once daily for 2 days or 1g once daily for 5 days
NOTES
Key: crm = cream; oint = ointment; RVVC = recurrent vulvovaginal candidiasis; supp = suppository; VVC = vulvovaginal candidiasis * Indicated to reduce the incidence of recurrent vulvovaginal candidiasis in females with a history of RVVC who are not of reproductive potential. † Do not dissolve in liquid. Sprinkle contents onto applesauce, yogurt or pudding and consume within 30mins. Do not chew; may follow with a glass of water. All products are for use on consecutive nights unless otherwise noted. Complete relief may take up to 7 days. Not an inclusive list of medications, official indications, and/or dosing details. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. (Rev. 4/2024)

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