Pneumococcal Vaccine Schedule: Adults

Key:CSF = cerebrospinal fluid; PCV = pneumococcal conjugate vaccine; PPSV = pneumococcal polysaccharide vaccine

 ¹ Also applies to receipt of PCV7 at any age and no other pneumococcal vaccines.

 ² The minimum interval for PPSV23 is ≥1yr since last PCV13 dose and ≥5yrs since last PPSV23 dose.

 ³ Based on shared clinical decision-making with the patient, vaccine providers may choose to administer PCV20 to those who have already completed the series with PCV13 and PPSV23.

 ⁴ Immunocompromising conditions include chronic renal failure, congenital or acquired asplenia, congenital or acquired immunodeficiency (eg, B- or T-lymphocyte deficiency, complement deficiencies [particularly C1, C2, C3, and C4 deficiencies], phagocytic disorders [excluding chronic granulomatous disease]), generalized malignancy, HIV infection, Hodgkin disease, iatrogenic immunosuppression (eg, treatment with immunosuppressants, including long-term systemic corticosteroids, radiation), leukemia, lymphoma, multiple myeloma, nephrotic syndrome, sickle cell disease/other hemoglobinopathies, solid organ transplant.

 ⁵ The minimum interval for PPSV23 is ≥8wks since last PCV13 dose and ≥5yrs since last PPSV23 dose in adults ≥65yrs with an immunocompromising condition, cochlear implant, or CSF leak, or in adults 19–64yrs with immunocompromising condition.

 ⁶ Review pneumococcal vaccine recommendations again when patient turns 65yrs old.

 ⁷ No vaccines recommended at this time.

 ⁸ Chronic medical conditions include alcoholism, chronic heart disease (eg, CHF, cardiomyopathies), chronic liver disease, chronic lung disease (eg, COPD, emphysema, asthma), cigarette smoking, diabetes.

 ⁹ Adults with chronic medical conditions were previously not recommended to receive PCV13.

Centers for Disease Control and Prevention. Pneumococcal Vaccine Timing for Adults. Accessed March 15, 2023. https://www.cdc.gov/vaccines/vpd/pneumo/downloads/pneumo-vaccine-timing.pdf.

Created 6/2023