Bowel Cleansers

BOWEL CLEANSERS
Generic	Strength	Brand		Form	Total Volume¹	Usual Dose
PEG FORMULATIONS
High Volume
polyethylene glycol 3350	60g/L	Colyte w. Flavor Packs	Rx	pwd for reconstitution (add 1 flavor pack before reconstitution)	4L oral	Adults: After fasting for ≥3hrs, 240mL orally every 10mins or 20–30mL/min by NG tube until fecal discharge is clear. Usual dose 3–4L. Only clear liq until exam. Children: Not established.
sodium chloride	1.46g/L
potassium chloride	0.745g/L
sodium bicarbonate	1.68g/L
sodium sulfate	5.68g/L
polyethylene glycol 3350	236g/4L	GoLytely	Rx	pwd for reconstitution	4L oral	Adults: May consume water or clear liq during and after completion of bowel prep up until 2hrs before procedure. 240mL orally every 10mins or 20–30mL/min by NG tube until rectal effluent is clear or 1 gallon consumed. Children: Not established.
sodium chloride	5.86g/4L
potassium chloride	2.97g/4L
sodium bicarbonate	6.74g/4L
sodium sulfate	22.74g/4L
polyethylene glycol 3350	420g/4L	NuLytely	Rx	pwd for reconstitution	4L oral	Adults: 240mL orally every 10mins or 20–30mL/min by NG tube until rectal effluent is clear or 4L consumed. Children: <6mos: Not recommended. ≥6mos: 25mL/kg/hr orally or by NG tube until rectal effluent is clear or 4L consumed. Both: May consume water or clear liq during and after completion of bowel prep up until 2hrs before procedure.
sodium bicarbonate	5.72g/4L
sodium chloride	11.2g/4L
potassium chloride	1.4g/4L
Low Volume
polyethylene glycol 3350	200g/2L	MoviPrep	Rx	pwd for reconstitution⁴	2L oral	Adults: Start the evening before colonoscopy. Split-dose regimen: drink 240mL every 15mins over 1hr until 1L consumed, follow with 480mL of clear liq; in the AM (start ≥3.5hrs before colonoscopy), drink 2nd liter over 1hr, then drink 480mL of clear liq ≥2hrs before colonoscopy. Evening-only regimen: start ≥3.5hrs before bedtime; drink 240mL every 15mins over 1hr until 1L consumed, then drink 2nd liter 1.5hrs later over 1hr; in addition, drink 1L of clear liq. Children: <18yrs: Not established.
sodium sulfate	15g/2L
sodium chloride	5.38g/2L
potassium chloride	2.03g/2L
ascorbic acid	9.4g/2L
sodium ascorbate	11.8g/2L
polyethylene glycol 3350	140g/32oz	Plenvu	Rx	pwd for reconstitution⁴	1L oral	Adults: Two-day regimen: start the evening before colonoscopy, drink 480mL over 30mins, follow with 480mL of clear liq over next 30mins; in the AM, drink 480mL over 30mins, then drink 480mL of clear liq over next 30mins. Consume additional water or clear liq up to 2hrs before colonoscopy. One-day regimen: start the morning of colonoscopy, drink 480mL over 30mins, follow with 480mL of clear liq over next 30mins. At minimum of 2hrs after first dose, drink 480mL over 30mins, follow with 480mL of clear liq over next 30mins. Consume additional water or clear liq up to 2hrs before colonoscopy. Children: Not established.
sodium ascorbate	48.11g/32oz
sodium sulfate	9g/32oz
ascorbic acid	7.54g/32oz
sodium chloride	5.2g/32oz
potassium chloride	2.2g/32oz
polyethylene glycol 3350	178.7g/L	Suflave	Rx	pwd for reconstitution	2L oral	Adults: Split-dose regimen: Dose 1 (start the evening before colonoscopy): 1 bottle with flavor enhancing packet. Drink 8oz soln every 15mins until empty; drink additional 16oz water during the PM; Dose 2 (start next morning and no sooner than 4hrs from starting Dose 1): repeat 2nd bottle with flavor enhancing packet. Drink additional 16oz water during the AM. Stop drinking liquids at least 2hrs prior to colonoscopy. Children: Not established.
sodium sulfate	7.3g/L
potassium chloride	1.12g/L
magnesium sulfate	0.9g/L
sodium chloride	0.5g/L
SODIUM PHOSPHATE FORMULATIONS
monobasic sodium phosphate	19g/197mL	Fleet Enema Extra				OTC	enema^2,3	197mL rectal	Adults: 1 enema rectally daily; may use up to 7 days. Results usually within 1-5mins; reevaluate if no relief after 7 days. Children: Use other forms.
dibasic sodium phosphate	7g/197mL	Fleet Enema Extra				OTC	enema^2,3	197mL rectal
OTHERS
bisacodyl	10mg/30mL	Fleet Bisacodyl Enema	OTC	enema²	30mL rectal	Adults: 1 enema rectally daily. Results usually within 5–20mins; reevaluate if ineffective. Children: Not recommended.
sodium picosulfate	10mg	Clenpiq	Rx	oral soln (undiluted)	320mL oral	Adults and Children: <9yrs: Not established. ≥9yrs: Split-dose regimen: take 1st dose during the evening before colonoscopy (eg, 5–9pm), followed by five or more 8oz cups of clear liq within 5hrs and before bed. Take 2nd dose the next day, start approx. 5hrs before colonoscopy, followed by at least four or more 8oz cups of clear liq up to 2hrs before the procedure.
magnesium oxide	3.5g
anhydrous citric acid	12g
sodium sulfate	1.479g	Sutab	Rx	tabs	—	Adults: Evening before colonoscopy: 12 tabs with 16oz of water over 15–20mins; approx. 1hr after the last tab, drink a second 16oz of water over 30mins; approx. 30mins after the second container of water, drink another 16oz of water over 30mins. Morning of colonoscopy (5–8hrs before procedure and no sooner than 4hrs from starting 1st dose): repeat using next 12 tabs. Complete prep ≥2hrs before colonoscopy. Children: Not established.
magnesium sulfate	0.225g
potassium chloride	0.188g
sodium sulfate	13.13g/4.5oz; 17.5g/6oz	Suprep	Rx	oral soln for dilution	32oz oral	Adults: Evening before colonoscopy: dilute 1 bottle (6oz) to 16oz with water and drink entire amount. Drink 32oz of water over the next hr. Next morning: repeat using the second bottle. Complete prep ≥2hrs before colonoscopy. Children: <12yrs: Not established. 12–16yrs: Evening before colonoscopy: dilute 1 bottle (4.5oz) to 12oz with water and drink entire amount. Drink 24oz of water over the next hr. Next morning: repeat using the second bottle. Complete prep ≥2hrs before colonoscopy.
potassium sulfate	2.35g/4.5oz; 3.13g/6oz
magnesium sulfate	1.2g/4.5oz; 1.6g/6oz
NOTES
Key: liq = liquid; oz = ounce; pkt = packet; pwd = powder; soln = solution ¹ Total volume per regimen; may be undiluted or after reconstitution/dilution ² Latex free ³ Contains sodium 4.4g/enema ⁴ Contains phenylalanine Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. (Rev. 1/2024)

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