Oral Allergy Treatments: OTC- MPR

Oral Allergy Treatments: OTC

ORAL ALLERGY TREATMENTS: OTC
Generic	Brand	Strength	Form	Dose
ANTIHISTAMINE (FIRST GENERATION H₁ ANTAGONIST)
chlorphenir– amine maleate	—	4mg	tabs	Children: <6yrs: not recommended. 6−11yrs: 2mg every 4−6hrs; max 12mg/24hrs. Adults: 4mg every 4−6hrs; max 24mg/24hrs.
clemastine fumarate	—	1.34mg	tabs	Children: <12yrs: not recommended. Adults: 1.34mg every 12hrs; max 2.68mg/day.
diphenhy– dramine HCl	Benadryl Allergy	25mg	tabs, liq-filled softgels ¹	Children: <6yrs: Individualize. 6−12yrs: 12.5−25mg every 4−6hrs; max 150mg/day. Adults: 25−50mg every 4−6hrs; max 300mg/day.
diphenhy– dramine HCl	Benadryl Allergy	12.5mg/ 5mL	liq ^1,2,3,5
ANTIHISTAMINE (SECOND GENERATION H₁ ANTAGONIST
cetirizine	Children’s Zyrtec Allergy Syrup	1mg/mL	syrup^1,3	Adults and Children: Dissolve tabs: May take with or without water. For doses <5mg: use syrup. <2yrs: not recommended. 2−6yrs: Initially 2.5mg once daily; max 5mg once daily or 2.5mg every 12hrs. ≥6yrs: Initially 5−10mg once daily. ≥65yrs: use dissolve tabs or syrup: 5mg once daily. Hepatic or renal impairment: Individualize.
	Children’s Zyrtec Dissolve Tabs	10mg	ODT
	Zyrtec	10mg	tabs
	Zyrtec Liquid Gels	10mg	liq-filled gels	Adults and Children: <6yrs: not recommended. ≥6yrs: 10mg once daily. Hepatic or renal impairment: Individualize
fexofenadine HCl	Allegra	60mg	tabs	Children: Use Children’s Allegra. Adults: 180mg once daily or 60mg twice daily. Renal impairment: Initially 60mg once daily.
	Allegra	180mg	tabs, gelcaps
	Children’s Allegra	30mg	ODT^4,5,6	Adults and Children: <6yrs: not recommended. Take on an empty stomach. Place tab on tongue and allow to disintegrate with or without water. 6–11yrs: 1 tab every 12hrs; max 2 tabs/24hrs. ≥12yrs: 2 tabs every 12hrs; max 4 tabs/24hrs.
	Children’s Allegra	30mg/ 5mL	susp⁵	Adults and Children: <2yrs: not recommended. 2–11yrs: 5mL every 12hrs; max 10mL/24hrs. ≥12yrs: 10mL every 12hrs; max 20mL/24hrs.
	Children’s Fexofenadine Tabs	30mg	tabs	Adults and Children: <6yrs: not recommended. 6–11yrs: 1 tab every 12hrs; max 2 tabs/24hrs. ≥12yrs: 2 tabs every 12hrs; max 4 tabs/24hrs.
levocetirizine dihydrochloride	Children’s Xyzal Allergy 24HR	2.5mg/ 5mL	liq soln⁵	Adults and Children: <2yrs: not recommended. 2–5yrs: max 1.25mg (2.5mL) once daily in the PM. 6–11yrs: max 2.5mg (5mL) once daily in the PM. ≥12yrs: 2.5mg–5mg (5−10mL) once daily in the PM based on symptom severity. Max: 5mg/day.
levocetirizine dihydrochloride	Xyzal Allergy 24HR	5mg	tabs
loratadine	Alavert ODT	10mg	ODT ⁴	Adults and Children: <6yrs: not recommended. ≥6yrs: Dissolve on tongue; swallow with or without water. 10mg once daily.
	Children’s Claritin	5mg	chew tabs^3,4	Adults and Children: <2yrs: not recommended. 2−5yrs: 5mg once daily. ≥6yrs: 10mg once daily or 5mg twice daily. Hepatic or renal insufficiency: See literature. RediTabs: Dissolve on tongue; swallow with or without water. Liqui‑Gels: Swallow whole.
	Children’s Claritin	1mg/mL	syrup ^1,2,3
	Claritin	10mg	tabs
	Claritin Liqui‑Gels	10mg	liquid-filled caps
	Claritin Reditabs 12-Hour	5mg	ODT
	Claritin Reditabs 24-Hour	10mg	ODT
ANTIHISTAMINE + SYMPATHOMIMETIC
cetirizine HCl/ pseudoephe– drine HCl	Zyrtec-D 12 Hour	5mg/ 120mg	ext‑rel tabs	Children: Not recommended. Adults: Swallow whole. 1 tab twice daily. Hepatic or renal impairment (CrCl ≤31mL/min): 1 tab once daily.
fexofenadine HCl/ pseudoephe– drine HCl	Allegra-D 12 Hour	60mg/ 120mg	ext‑rel tabs	Children: Not recommended. Adults: Swallow whole. Take on an empty stomach. 1 tab twice daily. Renal impairment: Initially 1 tab once daily.
fexofenadine HCl/ pseudoephe– drine HCl	Allegra‑D 24 Hour	180mg/ 240mg	ext‑rel tabs	Children: Not recommended. Adults: Swallow whole. Take on an empty stomach. 1 tab once daily. Renal insufficiency: Not recommended.
loratadine/ pseudoephe– drine sulfate	Alavert D‑12 Hour	5mg/ 120mg	ext‑rel tabs	Children: Not recommended. Adults: Swallow whole. 1 tab every 12hrs.
	Claritin‑D 12 Hour	5mg/ 120mg	ext‑rel tabs	Children: Not recommended. Adults: Swallow whole. 1 tab every 12hrs. Renal insufficiency (CrCl <30mL/min): 1 tab once daily.
	Claritin‑D 24 Hour	10mg/ 240mg	ext‑rel tabs	Children: Not recommended. Adults: Swallow whole. 1 tab daily. Renal insufficiency (CrCl <30mL/min): 1 tab every other day.
NOTES
Key: ext-rel = extended-release; liq = liquid; ODT = orally disintegrating tablets; susp = suspension; sust‑rel = sustained-release; ¹ dye-free; ² alcohol-free; ³ sugar-free; ⁴ contains phenylalanine; ⁵ contains sodium (see product monograph for sodium content); ⁶ contains lactose. Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. (Rev. 1/2023)

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