Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Renagel Generic Name & Formulations
Legal Class
Rx
General Description
Sevelamer HCl 800mg; tabs.
Pharmacological Class
Phosphate binder.
How Supplied
Tabs—180
Manufacturer
Generic Availability
YES
Renagel Indications
Indications
Control of serum phosphorus in patients with chronic kidney disease on dialysis.
Renagel Dosage and Administration
Adult
Swallow whole with meals. Patients not taking a phosphate binder: serum phosphorus >5.5 to <7.5mg/dL: 800mg 3 times daily; ≥7.5–<9mg/dL: 1.6g 3 times daily; ≥9mg/dL: 1.6g 3 times daily. Titrate by 1 tab per meal at 2-week intervals to keep serum phosphorus ≤5.5mg/dL. Switching from calcium acetate to sevelamer: see full labeling.
Children
Not established.
Renagel Contraindications
Contraindications
Bowel obstruction.
Renagel Boxed Warnings
Not Applicable
Renagel Warnings/Precautions
Warnings/Precautions
Dysphagia. Swallowing disorders; consider susp form. Severe GI motility disorders. Major GI tract surgery. Monitor serum bicarbonate, chloride. Monitor for reduced Vitamins D, E, K and folic acid levels; consider supplementation (esp. in pregnant and nursing mothers). Elderly. Pregnancy.
Renagel Pharmacokinetics
See Literature
Renagel Interactions
Interactions
Concomitant with drugs that have a narrow therapeutic index; monitor. Consider separation of administration with cyclosporine, tacrolimus, or levothyroxine. Separate dosing of ciprofloxacin by ≥2hrs before or 6hrs after sevelamer; mycophenolate mofetil by ≥2hrs before sevelamer. May decrease serum levels of fat soluble vitamins and folic acid.
Renagel Adverse Reactions
Adverse Reactions
Vomiting, nausea, diarrhea, dyspepsia, abdominal pain, flatulence, constipation; rare: bowel obstruction, perforation.
Renagel Clinical Trials
See Literature
Renagel Note
Not Applicable
Renagel Patient Counseling
See Literature
Images
