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Renacidin Irrigation Generic Name & Formulations
Legal Class
Rx
General Description
Citric acid 6.602g, glucono-delta-lactone 198mg, magnesium carbonate 3.177g; per 100mL; irrigation soln (pH 3.85).
Pharmacological Class
Irrigation solution.
How Supplied
Containers (500mL)—6
Manufacturer
Renacidin Irrigation Indications
Indications
Dissolution of renal or bladder calculi composed of apatite or struvite in select patients. Adjunct to dissolve apatite or struvite calculi after surgery or to achieve partial dissolution prior to surgical removal. Prevention of incrustations of indwelling urinary tract catheters.
Renacidin Irrigation Dosage and Administration
Adult
Renal calculi: Irrigate with sterile saline at 60mL/hr after fourth or fifth post-operative day and increase until pain, elevated pressure or a maximum of 120mL/hr is achieved; then start Renacidin at max rate achieved with saline. Bladder calculi: 30mL through urinary catheter into bladder, clamp for 30–60 minutes, drain bladder; repeat 4–6 times a day. Catheter incrustation: 30mL through catheter, clamp for 10 minutes, drain; repeat 3 times daily.
Renacidin Irrigation Contraindications
Contraindications
UTIs (obtain urine culture prior to use). Urinary tract extravasation.
Renacidin Irrigation Boxed Warnings
Not Applicable
Renacidin Irrigation Warnings/Precautions
Warnings/Precautions
Monitor magnesium, phosphate, serum creatinine, intrapelvic pressure, and for UTI or catheter obstruction; discontinue if these increase or severe urothelial edema on X-ray occur. Impaired renal function. Maintain catheter patency. Elderly. Pregnancy (Cat.C). Nursing mothers.
Renacidin Irrigation Pharmacokinetics
See Literature
Renacidin Irrigation Interactions
Interactions
Concomitant magnesium: not recommended.
Renacidin Irrigation Adverse Reactions
Adverse Reactions
Transient flank pain, urthelial ulceration and/or edema, fever, UTI, back pain, dysuria, transient hematuria, nausea, hypermagnesemia, hyperphosphatemia, elevated serum creatinine, candidiasis, bladder irritation.
Renacidin Irrigation Clinical Trials
See Literature
Renacidin Irrigation Note
Not Applicable
Renacidin Irrigation Patient Counseling
See Literature
