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Oxybutynin Chloride Syrup Generic Name & Formulations
Legal Class
Rx
General Description
Oxybutynin chloride 5mg/5mL.
Pharmacological Class
Antispasmodic/anticholinergic.
See Also
How Supplied
Contact supplier.
Manufacturer
Oxybutynin Chloride Syrup Indications
Indications
Symptoms of bladder instability associated with voiding in patients with uninhibited neurogenic or reflex neurogenic bladder (eg, urinary urgency, frequency, leakage, urge incontinence, dysuria).
Oxybutynin Chloride Syrup Dosage and Administration
Adult
5mg 2–3 times a day; max 20mg/day.
Children
<5yrs: not recommended. ≥5yrs: 5mg twice daily; max 15mg/day.
Oxybutynin Chloride Syrup Contraindications
Contraindications
Uncontrolled glaucoma. GI obstruction. Paralytic ileus. Intestinal atony in elderly or debilitated. Severe colitis. Myasthenia gravis. Megacolon. Toxic megacolon in ulcerative colitis. Obstructive uropathies. Unstable cardiovascular status in acute hemorrhage.
Oxybutynin Chloride Syrup Boxed Warnings
Not Applicable
Oxybutynin Chloride Syrup Warnings/Precautions
Warnings/Precautions
Activities requiring mental alertness. Diarrhea. Hepatic or renal disease. Autonomic neuropathy. Hyperthyroidism. Cardiovascular disease. Hiatal hernia. GI or GU obstruction. Ulcerative colitis. Exposure to extreme heat. Elderly. Pregnancy (Cat.B). Nursing mothers.
Oxybutynin Chloride Syrup Pharmacokinetics
See Literature
Oxybutynin Chloride Syrup Interactions
Interactions
Potentiates drowsiness with alcohol, other CNS depressants. Additive anticholinergic effects with other anticholinergics. May be potentiated by CYP3A4 inhibitors. Decreases GI motility, possibly affecting absorption of other drugs.
Oxybutynin Chloride Syrup Adverse Reactions
Adverse Reactions
Dry mouth, constipation, somnolence, headache, diarrhea, nausea, tachycardia, blurred vision, dry eyes, other anticholinergic effects.
Oxybutynin Chloride Syrup Clinical Trials
See Literature
Oxybutynin Chloride Syrup Note
Notes
Formerly known under the brand name Ditropan.
Oxybutynin Chloride Syrup Patient Counseling
See Literature
