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Tussionex Pennkinetic Generic Name & Formulations
Legal Class
CII
General Description
Hydrocodone bitartrate 10mg, chlorpheniramine maleate 8mg; per 5mL; as polistirex; ext-rel susp.
Pharmacological Class
Antitussive + antihistamine.
How Supplied
Susp—115mL
Manufacturer
Tussionex Pennkinetic Indications
Indications
Cough and upper respiratory symptoms associated with allergy or cold.
Tussionex Pennkinetic Dosage and Administration
Adult
Use accurate measuring device. ≥12yrs: 5mL every 12hrs; max 10mL/24hrs.
Children
Use accurate measuring device. <6yrs: see Contraindications. 6–11yrs: 2.5mL every 12hrs; max 5mL/24hrs.
Tussionex Pennkinetic Contraindications
Contraindications
Children <6yrs of age.
Tussionex Pennkinetic Boxed Warnings
Not Applicable
Tussionex Pennkinetic Warnings/Precautions
Warnings/Precautions
Risks from concomitant benzodiazepines or other CNS depressants (see Interactions). Respiratory depression esp. in children; discontinue if occurs. Post-op. Compromised respiratory function (eg, pulmonary disease). Abuse potential (monitor). Head injury, other intracranial lesions or pre-existing increase in intracranial pressure. Acute abdomen. Underlying intestinal motility disorders. Narrow-angle glaucoma. Asthma. Hypothyroidism. Addison’s disease. Prostatic hypertrophy. Urethral stricture. Severe hepatic or renal impairment. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.
Tussionex Pennkinetic Pharmacokinetics
See Literature
Tussionex Pennkinetic Interactions
Interactions
Increased risk of respiratory depression, sedation with benzodiazepines or other CNS depressants (eg, opioids, antihistamines, antipsychotics, anxiolytics, alcohol); avoid. May affect or be affected by MAOIs, TCAs. Paralytic ileus may occur with anticholinergics.
Tussionex Pennkinetic Adverse Reactions
Adverse Reactions
Nausea, vomiting, sedation, drowsiness, impairment of mental and physical performance, dysphoria, rash, pruritus; respiratory depression.
Tussionex Pennkinetic Clinical Trials
See Literature
Tussionex Pennkinetic Note
Not Applicable
Tussionex Pennkinetic Patient Counseling
See Literature
