Survanta Generic Name & Formulations
Legal Class
Rx
General Description
Beractant (as phospholipids) 25mg/mL; susp for intratracheal administration; preservative-free.
Pharmacological Class
Lung surfactant.
How Supplied
Vials (4mL, 8mL)—1
Manufacturer
Survanta Indications
Indications
Prevention and treatment of respiratory distress syndrome (RDS) in premature infants.
Survanta Dosage and Administration
Children
See literature for dosing chart, administration, and additional support procedures. 100mg of phospholipids (4mL)/kg birth weight per dose, by intratracheal administration; max 4 doses, at 6-hr intervals in the first 48hrs after birth. Rescue: give 1st dose as soon as possible after infant is placed on mechanical ventilation for treatment of RDS. Prevention: give 1st dose as soon as possible after birth, preferably within 15 mins. Avoid suctioning for 1 hour after treatment, unless significant airway obstruction occurs. Retreatment is determined by continued respiratory distress. Get radiographic confirmation of RDS in those infants given preventative dose before giving additional doses.
Survanta Contraindications
Not Applicable
Survanta Boxed Warnings
Not Applicable
Survanta Warnings/Precautions
Warnings/Precautions
Interrupt dosing if bradycardia or oxygen desaturation occurs; treat; resume after stabilization. Monitor oxygenation, carbon dioxide, and clinical condition frequently and carefully.
Survanta Pharmacokinetics
See Literature
Survanta Interactions
Not Applicable
Survanta Adverse Reactions
Adverse Reactions
Dosing procedure reactions including oxygen desaturation and bradycardia, rales, moist breath sounds, sepsis, intracranial hemorrhage.
Survanta Clinical Trials
See Literature
Survanta Note
Not Applicable
Survanta Patient Counseling
See Literature