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Striverdi Respimat Generic Name & Formulations
Legal Class
Rx
General Description
Olodaterol 2.5mcg; per actuation; inhalation spray; contains benzalkonium chloride.
Pharmacological Class
Long-acting beta-2 agonist (LABA).
How Supplied
Inhaler (w. cartridge)—4g (60 inh)
Manufacturer
Generic Availability
NO
Striverdi Respimat Indications
Indications
Long-term maintenance treatment of airflow obstruction in COPD, including chronic bronchitis and/or emphysema.
Limitations of Use
Not indicated to treat acute deteriorations of COPD or for treatment of asthma.
Striverdi Respimat Dosage and Administration
Adult
Take at same time each day. 2 inh once daily; max 2 inh/24hrs.
Children
Not established.
Striverdi Respimat Contraindications
Contraindications
Use of LABA without inhaled corticosteroid (ICS) in asthma.
Striverdi Respimat Boxed Warnings
Not Applicable
Striverdi Respimat Warnings/Precautions
Warnings/Precautions
LABA as monotherapy (without ICS) for asthma can increase risk of asthma-related events. Do not initiate in acute deteriorating COPD. Not for relief of acute symptoms. Prescribe a short-acting β2-agonist for acute symptoms; monitor for increased need. Do not exceed recommended dose. Discontinue if paradoxical bronchospasm or hypersensitivity reactions occur; use alternative therapy. Cardiovascular disease (esp. coronary insufficiency, arrhythmias, hypertrophic obstructive cardiomyopathy, hypertension). Convulsive disorders. Thyrotoxicosis. Prolongation of the QT interval. Hyperresponsiveness to sympathomimetics. Diabetes. Ketoacidosis. Risk of hypokalemia or hyperglycemia. Severe hepatic impairment. Pregnancy. Labor & delivery. Nursing mothers.
Striverdi Respimat Pharmacokinetics
See Literature
Striverdi Respimat Interactions
Interactions
Caution with concomitant other adrenergic drugs. Concomitant xanthine derivatives, steroids, K+-depleting diuretics may potentiate hypokalemia. Extreme caution with MAOIs, tricyclics, or drugs known to prolong QTc interval. Antagonized by β-blockers; if needed, consider cardioselective agents. Potentiated by strong CYP450 and P-gp inhibitors (eg, ketoconazole).
Striverdi Respimat Adverse Reactions
Adverse Reactions
Nasopharyngitis, URTI, bronchitis, UTI, cough, dizziness, rash, diarrhea, back pain, arthralgia.
Striverdi Respimat Clinical Trials
See Literature
Striverdi Respimat Note
Not Applicable
Striverdi Respimat Patient Counseling
See Literature
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