Lufyllin

— THERAPEUTIC CATEGORIES —
  • Asthma/COPD

Lufyllin Generic Name & Formulations

General Description

Dyphylline 200mg, 400mg; scored tabs.

Pharmacological Class

Xanthine.

How Supplied

Tabs—100

Manufacturer

Lufyllin Indications

Indications

For relief of acute bronchial asthma and for reversible bronchospasm associated with chronic bronchitis and emphysema.

Lufyllin Dosage and Administration

Adult

Individualize. Usual dose: up to 15mg/kg every 6 hours. Renal impairment: adjust dose.

Children

Not recommended.

Lufyllin Contraindications

Not Applicable

Lufyllin Boxed Warnings

Not Applicable

Lufyllin Warnings/Precautions

Warnings/Precautions

Not for primary treatment of acute attack. Severe cardiac disease. Hypertension. Hyperthyroidism. Acute myocardial injury. Peptic ulcer. Pregnancy (Cat.C). Nursing mothers.

Lufyllin Pharmacokinetics

See Literature

Lufyllin Interactions

Interactions

Toxicity with concomitant sympathomimetics. Potentiated by probenecid.

Lufyllin Adverse Reactions

Adverse Reactions

GI upset, epigastric pain, hematemesis, headache, irritability, restlessness, insomnia, hyperexcitability, agitation, muscle twitching, generalized clonic and tonic convulsions, palpitation, tachycardia, extrasystoles, flushing, hypotension, circulatory failure, ventricular arrhythmias, tachypnea, gross and microscopic hematuria, diuresis, hyperglycemia, inappropriate ADH syndrome.

Lufyllin Clinical Trials

See Literature

Lufyllin Note

Not Applicable

Lufyllin Patient Counseling

See Literature