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Ipratropium Bromide + Albuterol Sulfate Generic Name & Formulations
Legal Class
Rx
General Description
Ipratropium bromide 0.5 mg/3 mL (0.017%), albuterol (as sulfate) 2.5 mg/3 mL (0.083%); soln for inh.
Pharmacological Class
Anticholinergic + beta-2 agonist.
How Supplied
Contact supplier.
Manufacturer
Ipratropium Bromide + Albuterol Sulfate Indications
Indications
COPD when a second aerosol bronchodilator is needed.
Ipratropium Bromide + Albuterol Sulfate Dosage and Administration
Adult
≥18yrs: 1 vial by nebulizer 4–6 times daily.
Children
<18yrs: not recommended.
Ipratropium Bromide + Albuterol Sulfate Contraindications
Contraindications
Atropine allergy.
Ipratropium Bromide + Albuterol Sulfate Boxed Warnings
Not Applicable
Ipratropium Bromide + Albuterol Sulfate Warnings/Precautions
Warnings/Precautions
Not for primary treatment of acute attack. Avoid excessive use. Discontinue if paradoxical bronchospasm or cardiovascular effects occur. Cardiovascular disease (eg, coronary insufficiency, arrhythmias, hypertension). Hyperthyroidism. Diabetes. Seizure disorders. Narrow angle glaucoma. GI or GU obstruction. Hepatic or renal disease. Avoid eyes. Pregnancy (Cat.C). Labor & delivery. Nursing mothers: not recommended.
Ipratropium Bromide + Albuterol Sulfate Pharmacokinetics
See Literature
Ipratropium Bromide + Albuterol Sulfate Interactions
Interactions
Avoid MAOIs, tricyclics within 14 days (increased cardiovascular effects). Caution with other anticholinergics, sympathomimetics, drugs that lower potassium. Monitor digoxin. Antagonized by β-blockers.
Ipratropium Bromide + Albuterol Sulfate Adverse Reactions
Adverse Reactions
Lung disorders, pharyngitis, chest pain, GI disturbances, bronchitis, UTI, leg cramps, pain, voice changes, anticholinergic effects, nervousness, headache, dizziness, insomnia, tachycardia, hypokalemia, paradoxical bronchospasm.
Ipratropium Bromide + Albuterol Sulfate Clinical Trials
See Literature
Ipratropium Bromide + Albuterol Sulfate Note
Notes
Formerly known under the brand name DuoNeb.
Ipratropium Bromide + Albuterol Sulfate Patient Counseling
See Literature
