Fluticasone Nasal Spray

— THERAPEUTIC CATEGORIES —
  • Rhinitis/rhinorrhea (intranasal products)

Fluticasone Nasal Spray Generic Name & Formulations

General Description

Fluticasone propionate 50mcg/spray.

Pharmacological Class

Steroid.

How Supplied

Contact supplier.

Fluticasone Nasal Spray Indications

Indications

Perennial nonallergic rhinitis.

Fluticasone Nasal Spray Dosage and Administration

Adult

Initially 2 sprays in each nostril once daily or 1 spray in each nostril twice daily (AM and PM). Maintenance: may reduce to 1 spray in each nostril daily. Max total daily doses: 2 sprays in each nostril (200mcg/day).

Children

<4yrs: not established. ≥4yrs: initially 1 spray in each nostril once daily; may increase to 2 sprays in each nostril once daily. Maintenance: 1 spray in each nostril once daily. Max total daily doses: 2 sprays in each nostril (200mcg/day).

Fluticasone Nasal Spray Contraindications

Not Applicable

Fluticasone Nasal Spray Boxed Warnings

Not Applicable

Fluticasone Nasal Spray Warnings/Precautions

Warnings/Precautions

Maintain regular regimen. Respiratory tract tuberculosis. Infections (eg, ocular herpes simplex). If exposed to measles or chickenpox, consider anti-infective prophylactic therapy. If adrenal insufficiency exists following systemic corticosteroid therapy, replacement with topical corticosteroids may exacerbate symptoms of adrenal insufficiency (eg, depression). Monitor for hypercorticism and HPA axis suppression (if occurs, discontinue gradually), growth in children, IOP, glaucoma, or cataracts. Consider eye exams if ocular symptoms develop or in long-term use. Monitor for candida infection or other nasal mucosal changes. Avoid eyes. Pregnancy. Nursing mothers.

Fluticasone Nasal Spray Pharmacokinetics

See Literature

Fluticasone Nasal Spray Interactions

Interactions

Avoid ritonavir. Caution with potent CYP3A4 inhibitors (eg, ketoconazole).

Fluticasone Nasal Spray Adverse Reactions

Adverse Reactions

Headache, pharyngitis, epistaxis, nasal burning, asthma symptoms, GI upset, cough, reduced growth velocity in children.

Fluticasone Nasal Spray Clinical Trials

See Literature

Fluticasone Nasal Spray Note

Notes

Formerly known under the brand name Flonase.

Fluticasone Nasal Spray Patient Counseling

See Literature