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Curosurf Generic Name & Formulations
Legal Class
Rx
General Description
Poractant alfa (as phospholipids 80mg/mL and proteins 1mg/mL); susp for intratracheal administration; preservative-free.
Pharmacological Class
Lung surfactant.
How Supplied
Single-use vials (1.5mL, 3mL)—1
Manufacturer
Generic Availability
NO
Curosurf Indications
Indications
Treatment ("rescue") of respiratory distress syndrome (RDS) in premature infants.
Curosurf Dosage and Administration
Adult
Not applicable.
Children
See full labeling. Give by intratracheal administration through an endotracheal tube. Each dose should be administered as 2 aliquots. Initial dose of 2.5mL/kg birth weight; may give 2 more doses of 1.25mL/kg birth weight at 12-hour intervals.
Curosurf Contraindications
Not Applicable
Curosurf Boxed Warnings
Not Applicable
Curosurf Warnings/Precautions
Warnings/Precautions
Should only be administered by trained and experienced personnel in the care, resuscitation, and stabilization of pre-term infants. Perform frequent assessments so that oxygen and ventilatory support can be adjusted to respond to respiratory changes.
Curosurf Pharmacokinetics
See Literature
Curosurf Interactions
Not Applicable
Curosurf Adverse Reactions
Adverse Reactions
Bradycardia, hypotension, endotracheal tube blockage, oxygen desaturation.
Curosurf Clinical Trials
See Literature
Curosurf Note
Not Applicable
Curosurf Patient Counseling
See Literature
