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Combivent Respimat Generic Name & Formulations
Legal Class
Rx
General Description
Ipratropium bromide 20mcg, albuterol 100mcg (equivalent to 120mcg albuterol sulfate); per actuation; inhalation spray; CFC-free.
Pharmacological Class
Anticholinergic + beta-2 agonist.
How Supplied
Inhaler—4g (120 inh)
Manufacturer
Generic Availability
NO
Combivent Respimat Indications
Indications
COPD when a second aerosol bronchodilator is needed.
Combivent Respimat Dosage and Administration
Adult
1 inh 4 times daily; max 6 inh/day.
Children
Not established.
Combivent Respimat Contraindications
Contraindications
Atropine allergy.
Combivent Respimat Boxed Warnings
Not Applicable
Combivent Respimat Warnings/Precautions
Warnings/Precautions
Avoid excessive use. Discontinue if paradoxical bronchospasm occurs. Cardiovascular disorders. Arrhythmias. Hypertension. Diabetes. Hyperthyroidism. Seizure disorders. Sensitivity to sympthomimetic amines. Narrow angle glaucoma. GI or GU obstruction. Hepatic or renal disease. Pregnancy. Labor & delivery. Nursing mothers: not recommended.
Combivent Respimat Pharmacokinetics
See Literature
Combivent Respimat Interactions
Interactions
Extreme caution within 2 weeks of MAOIs or tricyclic antidepressants (increased cardiovascular effects). Caution with other anticholinergics, sympathomimetics, drugs that lower serum potassium. Antagonized by beta-blockers.
Combivent Respimat Adverse Reactions
Adverse Reactions
Upper respiratory infection, nasopharyngitis, cough, bronchitis, headache, dyspnea; paradoxical bronchospasm, urinary retention, hypokalemia, hypersensitivity reactions, ocular effects.
Combivent Respimat Clinical Trials
See Literature
Combivent Respimat Note
Not Applicable
Combivent Respimat Patient Counseling
See Literature
