Jornay Pm Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Manufacturer
Generic Availability
Mechanism of Action
Jornay Pm Indications
Indications
Jornay Pm Dosage and Administration
Adults and Children
Jornay Pm Contraindications
Contraindications
Jornay Pm Boxed Warnings
Boxed Warning
Abuse, misuse, and addiction.
Jornay Pm Warnings/Precautions
Warnings/Precautions
High potential for abuse, misuse, and addiction; assess patient’s risk before prescribing. Assess for presence of cardiac disease before initiating. Avoid in known structural cardiac abnormalities, cardiomyopathy, serious arrhythmias, coronary artery disease, or other cardiac disease. Pre-existing psychotic disorder. Bipolar disorder. Screen for risk factors of developing a manic episode prior to initiation. Consider discontinuing if new psychotic/manic symptoms occur. Risk for acute angle glaucoma. History of increased IOP or open angle glaucoma; monitor closely. Assess family history and evaluate for tics or Tourette’s syndrome before initiating; monitor for emergence or worsening, and discontinue if clinically appropriate. Peripheral vasculopathy, including Raynaud's phenomenon; monitor for digital changes. Monitor BP, HR, growth in children. Reduce dose or discontinue if paradoxical aggravation of symptoms occur. Reevaluate periodically. Pregnancy. Nursing mothers: monitor infants.
Jornay Pm Pharmacokinetics
Absorption
Median Tmax: 14 hours. Relative bioavailability vs methylphenidate immediate-release (given 3 times a day): 73.9%.
Elimination
Renal (90%). Half-life: ~5.9 hours.
Jornay Pm Interactions
Interactions
See Contraindications. Hypertensive crisis with MAOIs. May decrease effectiveness of antihypertensive agents; monitor and adjust dose of antihypertensives as needed. Concomitant halogenated anesthetics may increase the risk of sudden BP and HR increase during surgery; avoid use. Concomitant risperidone may increase risk of extrapyramidal symptoms; monitor.
Jornay Pm Adverse Reactions
Adverse Reactions
Appetite decreased, insomnia, nausea, vomiting, dyspepsia, abdominal pain, weight decreased, anxiety, dizziness, irritability, affect lability, tachycardia, BP increased; priapism, hypersensitivity, cardiovascular reactions, motor/verbal tics, glaucoma. Children also: headache, psychomotor hyperactivity, mood swings.
Jornay Pm Clinical Trials
See Literature
Jornay Pm Note
Notes
Jornay Pm Patient Counseling
See Literature