Fluphenazine Elixir

— THERAPEUTIC CATEGORIES —
  • Psychosis

Fluphenazine Elixir Generic Name & Formulations

General Description

Fluphenazine HCl 0.5mg/mL; alcohol 14%.

Pharmacological Class

Piperazine phenothiazine.

How Supplied

Contact supplier.

Fluphenazine Elixir Indications

Indications

Psychosis.

Fluphenazine Elixir Dosage and Administration

Adult

Initially: 2.5–10mg daily in 3–4 divided doses; max 40mg daily.

Children

Not recommended.

Fluphenazine Elixir Contraindications

Contraindications

Coma. CNS or bone marrow depression. Liver disease. Subcortical brain damage. Blood dyscrasias.

Fluphenazine Elixir Boxed Warnings

Not Applicable

Fluphenazine Elixir Warnings/Precautions

Warnings/Precautions

Cardiovascular or renal disease. Pheochromocytoma. Seizures. Glaucoma. History of breast cancer. Exposure to extreme heat or organophosphates. Gradually reduce to lowest effective maintenance dose. Monitor blood, liver, renal, and ocular function. Mental retardation. Surgery. Pregnancy. Nursing mothers.

Fluphenazine Elixir Pharmacokinetics

See Literature

Fluphenazine Elixir Interactions

Interactions

Potentiates anticholinergics, CNS depression with alcohol and other CNS depressants; both drugs with propranolol. Antagonized by anticholinergics. Decreased guanethidine effects. May cause false (+) pregnancy test.

Fluphenazine Elixir Adverse Reactions

Adverse Reactions

Drowsiness, anticholinergic and other autonomic effects, insomnia, restlessness, rash, photosensitivity, tardive dyskinesia, blood dyscrasias, jaundice, pneumonia, hypertension, retinopathy, lowered seizure threshold, extrapyramidal reactions, neuroleptic malignant syndrome, weight changes, endocrine effects.

Fluphenazine Elixir Clinical Trials

See Literature

Fluphenazine Elixir Note

Notes

Formerly known under the brand names Prolixin (tabs, concentrate, elixir, inj); Permitil (tabs, concentrate); Prolixin Decanoate (decanoate inj).

Fluphenazine Elixir Patient Counseling

See Literature