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Fluphenazine Decanoate Inj Generic Name & Formulations
Legal Class
Rx
General Description
Fluphenazine decanoate 25mg/mL; syringe; vial; contains benzyl alcohol.
Pharmacological Class
Piperazine phenothiazine.
How Supplied
Contact supplier.
Manufacturer
Fluphenazine Decanoate Inj Indications
Indications
Depot parenteral for psychosis.
Fluphenazine Decanoate Inj Dosage and Administration
Adult
Initially: 12.5–25mg IM or SC every 4–6 wks; max 100mg/dose.
Children
Not recommended.
Fluphenazine Decanoate Inj Contraindications
Contraindications
Coma. CNS or bone marrow depression. Liver disease. Subcortical brain damage. Blood dyscrasias.
Fluphenazine Decanoate Inj Boxed Warnings
Not Applicable
Fluphenazine Decanoate Inj Warnings/Precautions
Warnings/Precautions
Cardiovascular or renal disease. Pheochromocytoma. Seizures. Glaucoma. History of breast cancer. Exposure to extreme heat or organophosphates. Gradually reduce to lowest effective maintenance dose. Monitor blood, liver, renal, and ocular function. Mental retardation. Surgery. Pregnancy. Nursing mothers.
Fluphenazine Decanoate Inj Pharmacokinetics
See Literature
Fluphenazine Decanoate Inj Interactions
Interactions
Potentiates anticholinergics, CNS depression with alcohol and other CNS depressants; both drugs with propranolol. Antagonized by anticholinergics. Decreased guanethidine effects. May cause false (+) pregnancy test.
Fluphenazine Decanoate Inj Adverse Reactions
Adverse Reactions
Drowsiness, anticholinergic and other autonomic effects, insomnia, restlessness, rash, photosensitivity, tardive dyskinesia, blood dyscrasias, jaundice, pneumonia, hypertension, retinopathy, lowered seizure threshold, extrapyramidal reactions, neuroleptic malignant syndrome, weight changes, endocrine effects.
Fluphenazine Decanoate Inj Clinical Trials
See Literature
Fluphenazine Decanoate Inj Note
Notes
Formerly known under the brand names Prolixin (tabs, concentrate, elixir, inj); Permitil (tabs, concentrate); Prolixin Decanoate (decanoate inj).
Fluphenazine Decanoate Inj Patient Counseling
See Literature
