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Fluphenazine Concentrate Generic Name & Formulations
Legal Class
Rx
General Description
Fluphenazine HCl 5mg/mL; alcohol 14%. Dilute just before administration.
Pharmacological Class
Piperazine phenothiazine.
How Supplied
Contact supplier.
Manufacturer
Fluphenazine Concentrate Indications
Indications
Psychosis.
Fluphenazine Concentrate Dosage and Administration
Adult
Initially: 2.5–10mg daily in 3–4 divided doses; max 40mg daily.
Children
Not recommended.
Fluphenazine Concentrate Contraindications
Contraindications
Coma. CNS or bone marrow depression. Liver disease. Subcortical brain damage. Blood dyscrasias.
Fluphenazine Concentrate Boxed Warnings
Not Applicable
Fluphenazine Concentrate Warnings/Precautions
Warnings/Precautions
Cardiovascular or renal disease. Pheochromocytoma. Seizures. Glaucoma. History of breast cancer. Exposure to extreme heat or organophosphates. Gradually reduce to lowest effective maintenance dose. Monitor blood, liver, renal, and ocular function. Mental retardation. Surgery. Pregnancy. Nursing mothers.
Fluphenazine Concentrate Pharmacokinetics
See Literature
Fluphenazine Concentrate Interactions
Interactions
Potentiates anticholinergics, CNS depression with alcohol and other CNS depressants; both drugs with propranolol. Antagonized by anticholinergics. Decreased guanethidine effects. May cause false (+) pregnancy test.
Fluphenazine Concentrate Adverse Reactions
Adverse Reactions
Drowsiness, anticholinergic and other autonomic effects, insomnia, restlessness, rash, photosensitivity, tardive dyskinesia, blood dyscrasias, jaundice, pneumonia, hypertension, retinopathy, lowered seizure threshold, extrapyramidal reactions, neuroleptic malignant syndrome, weight changes, endocrine effects.
Fluphenazine Concentrate Clinical Trials
See Literature
Fluphenazine Concentrate Note
Notes
Formerly known under the brand names Prolixin (tabs, concentrate, elixir, inj); Permitil (tabs, concentrate); Prolixin Decanoate (decanoate inj).
Fluphenazine Concentrate Patient Counseling
See Literature
