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Dextroamphetamine Sulfate Tablets Generic Name & Formulations
Legal Class
CII
General Description
Dextroamphetamine sulfate 2.5mg, 5mg+, 7.5mg, 10mg+, 15mg, 20mg, 30mg; tabs; +scored.
Pharmacological Class
Amphetamine.
How Supplied
Contact supplier
Manufacturer
Dextroamphetamine Sulfate Tablets Indications
Indications
Attention deficit hyperactivity disorder.
Dextroamphetamine Sulfate Tablets Dosage and Administration
Adult
Not recommended.
Children
Avoid late evening doses; give first dose upon awakening and 1–2 more doses 4–6 hrs apart. <3yrs: not recommended. 3–5yrs: initially 2.5mg daily; may increase by 2.5mg at weekly intervals. ≥6yrs: initially 5mg 1–2 times daily; may increase by 5mg at weekly intervals; usual max 40mg/day.
Dextroamphetamine Sulfate Tablets Contraindications
Contraindications
Advanced arteriosclerosis. Cardiovascular disease. Moderate to severe hypertension. Hyperthyroidism. Glaucoma. Drug or alcohol abuse. Agitation. During or within 14 days of MAOIs. Hypersensitivity to sympathomimetics.
Dextroamphetamine Sulfate Tablets Boxed Warnings
Not Applicable
Dextroamphetamine Sulfate Tablets Warnings/Precautions
Warnings/Precautions
Tourette's syndrome. Psychosis. Mild hypertension. Seizure disorders. Monitor growth in children. Reevaluate need for therapy after drug-free interval. Prescribe limited quantity. Pregnancy (Cat.C). Nursing mothers: not recommended.
Dextroamphetamine Sulfate Tablets Pharmacokinetics
Elimination
Renal. Half-life: ~12 hours.
Dextroamphetamine Sulfate Tablets Interactions
Interactions
Hypertensive crisis with MAOIs: see Contraindications. Potentiated by urinary alkalinizers (eg, some thiazides), tricyclic antidepressants, propoxyphene. Potentiates meperidine, norepinephrine, phenobarbital, phenytoin. Antagonized by acidifiers, psychotropics, lithium. Antagonizes adrenergic blockers, sedatives, antihypertensives. Monitor phenytoin, ethosuximide, phenobarbital. Convulsions with propoxyphene overdose and amphetamines. May interfere with urinary steroid tests.
Dextroamphetamine Sulfate Tablets Adverse Reactions
Adverse Reactions
Hypertension, tachycardia, CNS overstimulation, dry mouth, GI disorders, anorexia, urticaria.
Dextroamphetamine Sulfate Tablets Clinical Trials
See Literature
Dextroamphetamine Sulfate Tablets Note
Notes
Formerly known under the brand name Dextrostat.
Dextroamphetamine Sulfate Tablets Patient Counseling
See Literature
Dextroamphetamine Sulfate Tablets Generic Name & Formulations
Legal Class
CII
General Description
Dextroamphetamine sulfate 2.5mg, 5mg+, 7.5mg, 10mg+, 15mg, 20mg, 30mg; tabs; +scored.
Pharmacological Class
Amphetamine.
How Supplied
Contact supplier
Manufacturer
Dextroamphetamine Sulfate Tablets Indications
Indications
Narcolepsy.
Dextroamphetamine Sulfate Tablets Dosage and Administration
Adult
Avoid late evening doses. 5–60mg daily in divided doses.
Children
Avoid late evening doses; give first dose upon awakening and 1–2 more doses 4–6hrs apart. <6yrs: not recommended. 6–12yrs: initially 5mg daily; may increase by 5mg/day at weekly intervals. ≥12yrs: initially 10mg daily; may increase by 10mg/day at weekly intervals.
Dextroamphetamine Sulfate Tablets Contraindications
Contraindications
Advanced arteriosclerosis. Cardiovascular disease. Moderate to severe hypertension. Hyperthyroidism. Glaucoma. Drug or alcohol abuse. Agitation. During or within 14 days of MAOIs. Hypersensitivity to sympathomimetics.
Dextroamphetamine Sulfate Tablets Boxed Warnings
Not Applicable
Dextroamphetamine Sulfate Tablets Warnings/Precautions
Warnings/Precautions
Tourette's syndrome. Psychosis. Mild hypertension. Seizure disorders. Monitor growth in children. Reevaluate need for therapy after drug-free interval. Prescribe limited quantity. Pregnancy (Cat.C). Nursing mothers: not recommended.
Dextroamphetamine Sulfate Tablets Pharmacokinetics
Elimination
Renal. Half-life: ~12 hours.
Dextroamphetamine Sulfate Tablets Interactions
Interactions
Hypertensive crisis with MAOIs: see Contraindications. Potentiated by urinary alkalinizers (eg, some thiazides), tricyclic antidepressants, propoxyphene. Potentiates meperidine, norepinephrine, phenobarbital, phenytoin. Antagonized by acidifiers, psychotropics, lithium. Antagonizes adrenergic blockers, sedatives, antihypertensives. Monitor phenytoin, ethosuximide, phenobarbital. Convulsions with propoxyphene overdose and amphetamines. May interfere with urinary steroid tests.
Dextroamphetamine Sulfate Tablets Adverse Reactions
Adverse Reactions
Hypertension, tachycardia, CNS overstimulation, dry mouth, GI disorders, anorexia, urticaria.
Dextroamphetamine Sulfate Tablets Clinical Trials
See Literature
Dextroamphetamine Sulfate Tablets Note
Notes
Formerly known under the brand name Dextrostat.
Dextroamphetamine Sulfate Tablets Patient Counseling
See Literature
