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Advil Pm Liqui-gels Generic Name & Formulations
Legal Class
OTC
General Description
Ibuprofen (solubilized) 200mg, diphenhydramine HCl 25mg.
Pharmacological Class
NSAID + hypnotic (anticholinergic).
See Also
How Supplied
Caplets—2, 20, 40, 80, 120 (orig or EZ open), 200; Liqui-Gels—20, 40, 80
Manufacturer
Advil Pm Liqui-gels Indications
Indications
Relief of occasional sleeplessness when associated with minor aches and pains.
Advil Pm Liqui-gels Dosage and Administration
Adult
2 caplets or liqui-gels at bedtime. Max 2 caplets or liqui-gels/24hrs.
Children
<12yrs: not recommended.
Advil Pm Liqui-gels Contraindications
Contraindications
Aspirin allergy. Unless sufficient time for a full night's sleep. Immediately before or after cardiac surgery. Sleeplessness without pain. Concomitant with other diphenhydramine-containing products (including topicals).
Advil Pm Liqui-gels Boxed Warnings
Not Applicable
Advil Pm Liqui-gels Warnings/Precautions
Warnings/Precautions
Increased risk of severe stomach bleeding (esp. ≥60yrs old). History of GI disorders (eg, heartburn, bleeding ulcers). Respiratory disorders (eg, emphysema, bronchitis). Increased risk of heart attack or failure, and stroke. Hypertension. Heart disease. Recent stroke. Liver cirrhosis. Renal disease. Asthma. Glaucoma. GI or urinary obstruction. Reevaluate if pain persists or worsens after >10 days or sleeplessness persists continuously >2 weeks. Elderly. Pregnancy (esp. during ≥20 weeks): not recommended. Nursing mothers.
Advil Pm Liqui-gels Pharmacokinetics
See Literature
Advil Pm Liqui-gels Interactions
Interactions
Avoid aspirin or other pain relievers. Increased risk of GI bleed with anticoagulants, corticosteroids, other OTC or Rx NSAID-containing products (eg, ibuprofen, naproxen, others), ≥3 alcoholic drinks/day, or prolonged use. Caution with diuretics. Additive effects with other antihistamines, anticholinergics, sedatives, tranquilizers, or any other sleep-aid.
Advil Pm Liqui-gels Adverse Reactions
Adverse Reactions
Drowsiness, GI upset/bleed, rash, symptoms of heart problems or stroke (eg, trouble breathing, feel faint, slurred speech), redness, swelling, allergic reactions; discontinue if occur.
Advil Pm Liqui-gels Clinical Trials
See Literature
Advil Pm Liqui-gels Note
Not Applicable
Advil Pm Liqui-gels Patient Counseling
See Literature
