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Nicotrol Ns Generic Name & Formulations
Legal Class
Rx
General Description
Nicotine 0.5mg/spray; aqueous nasal spray.
See Also
How Supplied
Inhaler 168 cartridges—1 (w. mouthpieces and case); Nasal Spray 10mL (200 sprays)—4 (w. metered spray pump)
Manufacturer
Nicotrol Ns Indications
Indications
Adjunct in smoking cessation therapy.
Nicotrol Ns Dosage and Administration
Adult
Do not sniff, swallow, or inhale. Individualize. Usually 1–2 doses/hour; max 5 doses/hour, 40 doses/day for up to 3 months; may discontinue abruptly or taper.
Children
Not recommended.
Nicotrol Ns Contraindications
Contraindications
Concurrent smoking or other nicotine products.
Nicotrol Ns Boxed Warnings
Not Applicable
Nicotrol Ns Warnings/Precautions
Warnings/Precautions
Sustained use (>6 months): not recommended. Avoid immediately post-MI, in arrhythmias, or severe or worsening angina pectoris. Hypertension. Vasospastic or coronary heart disease. Bronchospastic disease. Severe reactive airway disease: not recommended. Hepatic or moderate/severe renal impairment. Hyperthyroidism. Pheochromocytoma. Diabetes. Esophagitis. Active gastric or peptic ulcers. Elderly. Low doses may be toxic to children and pets. Nasal Spray: nasal mucosal disorders. Pregnancy, labor & delivery: not recommended (attempt nondrug treatment first). Nursing mothers.
Nicotrol Ns Pharmacokinetics
See Literature
Nicotrol Ns Interactions
Interactions
Nasal Spray antagonized by nasal vasoconstrictors (eg, xylometazoline). Smoking cessation potentiates theophylline, insulin, β-blockers, pentazocine, oxazepam, tricyclic antidepressants (eg, imipramine), caffeine, acetaminophen, adrenergic antagonists (eg, prazosin, labetalol), others. Smoking cessation antagonizes adrenergic agonists (eg, isoproterenol, phenylephrine), others.
Nicotrol Ns Adverse Reactions
Adverse Reactions
Local irritation, nausea, diarrhea, hiccup, dyspepsia, headache, dizziness, palpitations, hypertension.
Nicotrol Ns Clinical Trials
See Literature
Nicotrol Ns Note
Not Applicable
Nicotrol Ns Patient Counseling
See Literature
