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Nicotrol Inhaler Generic Name & Formulations
Legal Class
Rx
General Description
Nicotine inhalation system 10mg (4mg delivered); per cartridge; contains menthol.
See Also
How Supplied
Inhaler 168 cartridges—1 (w. mouthpieces and case); Nasal Spray 10mL (200 sprays)—4 (w. metered spray pump)
Manufacturer
Nicotrol Inhaler Indications
Indications
Adjunct in smoking cessation therapy.
Nicotrol Inhaler Dosage and Administration
Adult
Each cartridge lasts about 20 minutes with frequent continuous puffing and provides nicotine equivalent to about 2 cigarettes. Individualize. Use at least 6 cartridges/day for 1st 3–6 weeks; max 16 cartridges/day for 1st 12 weeks, then reduce gradually over 12 more weeks.
Children
Not recommended.
Nicotrol Inhaler Contraindications
Contraindications
Concurrent smoking or other nicotine products.
Nicotrol Inhaler Boxed Warnings
Not Applicable
Nicotrol Inhaler Warnings/Precautions
Warnings/Precautions
Sustained use (>6 months): not recommended. Avoid immediately post-MI, in arrhythmias, or severe or worsening angina pectoris. Hypertension. Vasospastic or coronary heart disease. Bronchospastic disease. Severe reactive airway disease: not recommended. Hepatic or moderate/severe renal impairment. Hyperthyroidism. Pheochromocytoma. Diabetes. Esophagitis. Active gastric or peptic ulcers. Elderly. Low doses may be toxic to children and pets. Nasal Spray: nasal mucosal disorders. Pregnancy, labor & delivery: not recommended (attempt nondrug treatment first). Nursing mothers.
Nicotrol Inhaler Pharmacokinetics
See Literature
Nicotrol Inhaler Interactions
Interactions
Nasal Spray antagonized by nasal vasoconstrictors (eg, xylometazoline). Smoking cessation potentiates theophylline, insulin, β-blockers, pentazocine, oxazepam, tricyclic antidepressants (eg, imipramine), caffeine, acetaminophen, adrenergic antagonists (eg, prazosin, labetalol), others. Smoking cessation antagonizes adrenergic agonists (eg, isoproterenol, phenylephrine), others.
Nicotrol Inhaler Adverse Reactions
Adverse Reactions
Local irritation, nausea, diarrhea, hiccup, dyspepsia, headache, dizziness, palpitations, hypertension.
Nicotrol Inhaler Clinical Trials
See Literature
Nicotrol Inhaler Note
Not Applicable
Nicotrol Inhaler Patient Counseling
See Literature
