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Digifab Generic Name & Formulations
Legal Class
Rx
General Description
Digoxin Immune Fab (ovine) 40mg/vial; IV inj after reconstitution; preservative-free.
Pharmacological Class
Digoxin binder.
How Supplied
Single-use vial—1
Manufacturer
Digifab Indications
Indications
Digoxin toxicity or overdose.
Digifab Dosage and Administration
Adults and Children
See literature. Dose based on amount of digoxin or digitoxin to be neutralized. Contents of 1 vial neutralizes 0.5mg digoxin.
Digifab Contraindications
Not Applicable
Digifab Boxed Warnings
Not Applicable
Digifab Warnings/Precautions
Warnings/Precautions
Previous allergies to antibiotics, sheep antibodies, papain or papaya extracts. Monitor potassium, renal, and cardiac function. Postpone redigitalization until Fab fragments cleared. Interferes with digitalis immunoassays. Pregnancy (Cat.C). Nursing mothers.
Digifab Pharmacokinetics
See Literature
Digifab Interactions
Not Applicable
Digifab Adverse Reactions
Adverse Reactions
Symptoms of digoxin withdrawal. Hypokalemia.
Digifab Clinical Trials
See Literature
Digifab Note
Not Applicable
Digifab Patient Counseling
See Literature
