Vecuronium Bromide For Injection

<7wks: not recommended. Individualize. >7wks–10yrs: see literature. ≥10yrs: Relaxation for intubation: inject bolus dose of 0.08–0.1mg/kg; may reduce dose to 0.06–0.085mg/kg if given >5 minutes after start of inhalation agent or when steady state has been achieved. Give 1microgram/kg/min (range: 0.8–1.2microgram/kg/min) by continuous IV infusion 20–40 minutes after initial dose. Inhalation anesthetics (eg, enflurane, isoflurane): reduce infusion rate 25–60%, 45–60 minutes after initial dose. Intubation with succinylcholine: reduce initial vecuronium dose to 0.04–0.06mg/kg with inhalation anesthesia; and to 0.05–0.06mg/kg with balanced anesthesia. Prolonged surgery: maintenance dose of 0.01–0.015mg/kg, within 25–40 minutes of initial dose. During surgery under halothane anesthesia: initial dosing range from 0.15mg/kg up to 0.28mg/kg have been given. Monitor with a peripheral nerve stimulator to avoid overdosage.