Qutenza Generic Name & Formulations
Legal Class
Rx
General Description
Capsaicin 8% (179mg); patch.
Pharmacological Class
TRPV1 channel agonist.
How Supplied
Patch—1, 2 (both with 50g tube of Cleansing Gel)
Manufacturer
Qutenza Indications
Indications
Neuropathic pain associated with post-herpetic neuralgia (PHN) or with diabetic peripheral neuropathy (DPN) of the feet.
Qutenza Dosage and Administration
Adult
Identify treatment area and mark the skin; may cut patches to match size and shape of area. Pretreat with topical anesthetic to reduce discomfort, once anesthetized, remove anesthetic and wash the treatment area. Administer in a well-ventilated area. Apply to dry, intact skin within 2hrs of opening patch. Apply patch (up to 4 may be used) for 60mins (PHN) or 30mins (DPN); may repeat every 3 months or as warranted by the return of pain (not more frequently than every 3 months). May use a dressing to ensure patch remains in contact with treatment area. After removal of patch, apply Cleansing Gel to area and leave on for at least one minute. Remove Cleansing Gel with dry wipe; wash and dry the area. Treat acute pain during and following the procedure with local cooling and/or analgesics. Use nitrile gloves, face mask, and protective glasses when handling patch and cleaning capsaicin residue from skin. Immediately dispose of patches.
Children
<18yrs: not established.
Qutenza Contraindications
Not Applicable
Qutenza Boxed Warnings
Not Applicable
Qutenza Warnings/Precautions
Warnings/Precautions
Should only be administered by a physician or healthcare professional. Severe irritation with unintended exposure (eg, eyes, mucous membranes, respiratory tract, skin). Aerosolization of capsaicin may occur with rapid removal of patches; remove patches slowly by rolling the adhesive side inward. DPN: examine feet for skin lesions related to underlying neuropathy or vascular insufficiency prior to each application. Evaluate for recent history of cardio- and cerebrovascular disease. Monitor BP periodically during treatment. Preexisting sensory deficits: assess for sensory deterioration or loss prior to each application; reconsider treatment if detected or worsens. Pregnancy. Nursing mothers.
Qutenza Pharmacokinetics
See Literature
Qutenza Interactions
Not Applicable
Qutenza Adverse Reactions
Adverse Reactions
Application site reactions (eg, erythema, pain, pruritus, papules); increased blood pressure.
Qutenza Clinical Trials
See Literature
Qutenza Note
Not Applicable
Qutenza Patient Counseling
See Literature
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