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Prilocaine Hcl Generic Name & Formulations
Legal Class
Rx
General Description
Prilocaine HCl 40mg/mL; soln for inj.
Pharmacological Class
Local anesthetic (amide-type).
How Supplied
Contact supplier.
Manufacturer
Prilocaine Hcl Indications
Indications
Local anesthesia in dentistry by nerve block or infiltration techniques.
Prilocaine Hcl Dosage and Administration
Adult
Maxillary infiltration: initially 1–2mL; max recommended dose within a 2-hour period: <70kg: 8mg/kg; ≥70kg: 600mg. Elderly, debilitated, acutely ill: reduce dose.
Children
<10yrs: use Clarks rule to calculate dose.
Prilocaine Hcl Contraindications
Contraindications
Congenital or idiopathic methemoglobinemia.
Prilocaine Hcl Boxed Warnings
Not Applicable
Prilocaine Hcl Warnings/Precautions
Warnings/Precautions
Have resuscitative equipment, oxygen, and standard protocol for management of malignant hyperthermia available. G6PD deficiency. Severe shock. Heart block. Hepatic disease. Impaired cardiovascular function. Head and neck block. Monitor cardiovascular and respiratory vital signs. Pregnancy (Cat.B). Nursing mothers.
Prilocaine Hcl Pharmacokinetics
See Literature
Prilocaine Hcl Interactions
Interactions
Risk of methemoglobinemia with sulfonamides, acetaminophen, acetanilid, aniline dyes, benzocaine, chloroquine, dapsone, naphthalene, nitrates and nitrites, nitrofurantoin, nitroglycerin, nitroprusside, pamaquine, para-aminosalicylic acid, phenacetin, phenobarbital, phenytoin, primaquine, quinine.
Prilocaine Hcl Adverse Reactions
Adverse Reactions
Swelling and persistent paresthesia of lips, oral tissue; CNS effects (eg, excitation, depression, restlessness, anxiety, dizziness, tremors), cardiovascular effects (eg, bradycardia, hypotension, cardiovascular collapse), allergic-type reactions, neurologic effects, increased creatinine phosphokinase.
Prilocaine Hcl Clinical Trials
See Literature
Prilocaine Hcl Note
Notes
Formerly known under the brand name Citanest Plain Dental.
Prilocaine Hcl Patient Counseling
See Literature
