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Chlorzoxazone Generic Name & Formulations
Legal Class
Rx
General Description
Chlorzoxazone 375mg, 500mg+, 750mg+; tabs; +scored.
Pharmacological Class
Muscle relaxant (central).
How Supplied
Contact supplier
Manufacturer
Chlorzoxazone Indications
Indications
As adjunct to rest, physical therapy, and other measures in acute, painful musculoskeletal conditions.
Chlorzoxazone Dosage and Administration
Adult
250–500mg 3–4 times daily. Painful musculoskeletal conditions: initially 500mg 3–4 times daily. May increase to 750mg 3–4 times daily if inadequate response. May reduce dose based on improvement.
Children
Not recommended.
Chlorzoxazone Contraindications
Contraindications
Known drug intolerance.
Chlorzoxazone Boxed Warnings
Not Applicable
Chlorzoxazone Warnings/Precautions
Warnings/Precautions
Monitor for hepatotoxicity; discontinue if hepatic dysfunction or abnormal liver enzymes develop. Known allergies or history of. Discontinue if sensitivity reaction occurs. Pregnancy.
Chlorzoxazone Pharmacokinetics
See Literature
Chlorzoxazone Interactions
Interactions
Additive effects with concomitant alcohol, other CNS depressants.
Chlorzoxazone Adverse Reactions
Adverse Reactions
Drowsiness, dizziness, lightheadedness, malaise, overstimulation; rare: skin rash, petechiae, ecchymosis, fatal hepatocellular toxicity.
Chlorzoxazone Clinical Trials
See Literature
Chlorzoxazone Note
Notes
Formerly known under the brand name Lorzone, Paraflex, Parafon Forte DSC.
Chlorzoxazone Patient Counseling
See Literature
