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Carisoprodol/aspirin/codeine Generic Name & Formulations
Legal Class
CIII
General Description
Carisoprodol 200mg, aspirin 325mg, codeine phosphate 16mg; tabs; contains sulfites.
Pharmacological Class
Muscle relaxant (central) + salicylate + opioid.
How Supplied
Contact supplier.
Manufacturer
Carisoprodol/aspirin/codeine Indications
Indications
Relief of painful musculoskeletal conditions.
Carisoprodol/aspirin/codeine Dosage and Administration
Adult
1–2 tabs 4 times daily. May treat up to 2–3 weeks.
Children
<16yrs: not established.
Carisoprodol/aspirin/codeine Contraindications
Contraindications
GI complication (eg, bleeding, perforation, obstruction) due to aspirin use. Aspirin-induced asthma. Carbamate sensitivity. NSAID allergy. Porphyria. Post-op pain management in children who have undergone tonsillectomy and/or adenoidectomy.
Carisoprodol/aspirin/codeine Boxed Warnings
Not Applicable
Carisoprodol/aspirin/codeine Warnings/Precautions
Warnings/Precautions
Risk of respiratory depression and death related to ultra-rapid metabolizers of codeine (esp. children in post-op tonsillectomy and/or adenoidectomy). Peptic ulcer. Gastritis. Acute abdominal conditions. Pancreatic or biliary duct disease. Renal or hepatic dysfunction. History of drug abuse. Asthma. COPD. Lung disease. Increased intracranial pressure. Dehydration. Use lowest effective dose for shortest duration. Elderly. Debilitated. Pregnancy (Cat.D). Nursing mothers: not recommended.
Carisoprodol/aspirin/codeine Pharmacokinetics
See Literature
Carisoprodol/aspirin/codeine Interactions
Interactions
Additive effects with alcohol, CNS depressants, oral anticoagulants, hypoglycemics and plasma bound drugs (eg, methotrexate); use caution. Alcohol, NSAIDs, and oral anticoagulants increase risk of GI bleeding. May reduce antihypertensive effects with concomitant ACEIs, ARBs, beta-blockers, diuretics. Uricosurics antagonized. Urine alkalinizers or acidifiers decrease or increase, respectively, aspirin levels.
Carisoprodol/aspirin/codeine Adverse Reactions
Adverse Reactions
Dizziness, drowsiness, vertigo, ataxia, GI upset or bleeding, epigastric discomfort, tachycardia, orthostatic hypotension, facial flushing, rash, tinnitus; respiratory depression, hypotension.
Carisoprodol/aspirin/codeine Clinical Trials
See Literature
Carisoprodol/aspirin/codeine Note
Notes
Formerly known under the brand name Soma Compound w. Codeine.
Carisoprodol/aspirin/codeine Patient Counseling
See Literature
