Butorphanol Nasal Spray Generic Name & Formulations
Legal Class
CIV
General Description
Butorphanol tartrate 1mg/spray; nasal spray.
Pharmacological Class
Opioid (agonist-antagonist).
How Supplied
Nasal Spray 2.5mL (8–15 sprays)—Contact supplier.
Manufacturer
Butorphanol Nasal Spray Indications
Indications
Pain management when opioid analgesia is appropriate.
Butorphanol Nasal Spray Dosage and Administration
Adult
≥18 years: initially 1 spray in 1 nostril, repeat after 60–90 minutes if needed (Elderly: 90–120 minutes); may repeat in 3–4 hours. Or, may give 1 spray in each nostril, may repeat after 3–4 hours.
Children
<18 years: not recommended.
Butorphanol Nasal Spray Contraindications
Not Applicable
Butorphanol Nasal Spray Boxed Warnings
Not Applicable
Butorphanol Nasal Spray Warnings/Precautions
Warnings/Precautions
Head injury. Increased intracranial pressure. Biliary tract surgery. Respiratory, cardiac, renal, or hepatic dysfunction. MI. Ventricular dysfunction. Coronary insufficiency. Hypertension. May precipitate withdrawal in narcotic addicts. Elderly. Labor & delivery. Pregnancy (Cat.C). Nursing mothers.
Butorphanol Nasal Spray Pharmacokinetics
See Literature
Butorphanol Nasal Spray Interactions
Interactions
Potentiates CNS depression with alcohol, other CNS depressants. Nasal vasoconstrictors delay onset. May be antagonized by concomitant (within 30 minutes) sumatriptan nasal spray.
Butorphanol Nasal Spray Adverse Reactions
Adverse Reactions
Sedation, dizziness, nasal congestion, insomnia, GI upset, respiratory depression, sweating, hypo- or hypertension, rash, vasodilation, palpitation, tinnitus, respiratory and CNS effects.
Butorphanol Nasal Spray Clinical Trials
See Literature
Butorphanol Nasal Spray Note
Notes
Formerly known under the brand name Stadol NS.
Butorphanol Nasal Spray Patient Counseling
See Literature