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Periostat Generic Name & Formulations
Legal Class
Rx
General Description
Doxycycline hyclate 20mg; tabs.
Pharmacological Class
Tetracycline antibiotic.
How Supplied
Tabs—60, 100
Manufacturer
Periostat Indications
Indications
As an adjunct to scaling and root planing to promote attachment level gain and to reduce pocket depth in patients with adult periodontitis.
Periostat Dosage and Administration
Adult
Take on an empty stomach with adequate amount of fluid. 20mg twice daily (in AM and PM). May give up to 9 months.
Children
Not recommended.
Periostat Contraindications
Contraindications
Nursing mothers. Infants. Children.
Periostat Boxed Warnings
Not Applicable
Periostat Warnings/Precautions
Warnings/Precautions
History of or active oral candidiasis. Monitor blood, renal, and hepatic function in long-term use. Avoid sun and UV light. Pregnancy (Cat.D): not recommended.
Periostat Pharmacokinetics
See Literature
Periostat Interactions
Interactions
Avoid concomitant penicillins, methoxyflurane. Antacids, iron, zinc, calcium, magnesium, urinary alkalinizers reduce absorption. Carbamazepine, barbiturates, phenytoin may decrease effectiveness. Monitor prothrombin time with oral anticoagulants. Oral contraceptives may be less effective.
Periostat Adverse Reactions
Adverse Reactions
Photosensitivity, GI upset, rash, blood dyscrasias; rare: hepatotoxicity.
Periostat Clinical Trials
See Literature
Periostat Note
Not Applicable
Periostat Patient Counseling
See Literature
