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Yutiq Generic Name & Formulations
Legal Class
Rx
General Description
Fluocinolone acetonide 0.18mg; implant for intravitreal inj.
Pharmacological Class
Steroid.
How Supplied
Single-use applicator—1 (w. needle)
Manufacturer
Generic Availability
NO
Mechanism of Action
Corticosteroids inhibit inflammatory responses to a variety of inciting agents including multiple inflammatory cytokines. Corticosteroids are thought to act by inhibition of phospholipase A2 via induction of inhibitory proteins collectively called lipocortins. It is postulated that these proteins control biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting release of the common precursor, arachidonic acid.
Yutiq Indications
Indications
Chronic non-infectious posterior segment uveitis.
Yutiq Dosage and Administration
Adult
Give by intravitreal inj. See full labeling for administration.
Children
Not established.
Yutiq Contraindications
Contraindications
Ocular or periocular infections.
Yutiq Boxed Warnings
Not Applicable
Yutiq Warnings/Precautions
Warnings/Precautions
Monitor for increased IOP and endophthalmitis; may include check for perfusion of the optic nerve head immediately, tonometry within 30 mins, and biomicroscopy between 2–7 days post injection. Risk of secondary ocular infections (eg, bacterial, fungal, viral). History of ocular herpes simplex: not recommended. Risk of implant migration if absent or torn posterior capsule of the lens. Pregnancy. Nursing mothers.
Yutiq Pharmacokinetics
See Literature
Yutiq Interactions
Not Applicable
Yutiq Adverse Reactions
Adverse Reactions
Cataract development, increased IOP; injection-related effects (eg, endophthalmitis, eye inflammation, choroidal/retinal detachments), glaucoma, others.
Yutiq Clinical Trials
See Literature
Yutiq Note
Not Applicable
Yutiq Patient Counseling
See Literature
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