Vyzulta Generic Name & Formulations
Legal Class
Rx
General Description
Latanoprostene bunod 0.024%; oph soln; contains benzalkonium chloride.
Pharmacological Class
Prostaglandin analogue.
How Supplied
Soln—5mL
Manufacturer
Generic Availability
NO
Vyzulta Indications
Indications
Open-angle glaucoma. Ocular hypertension.
Vyzulta Dosage and Administration
Adult
>16yrs: instill 1 drop in the affected eye(s) once daily in the PM.
Children
≤16yrs: not recommended.
Vyzulta Contraindications
Not Applicable
Vyzulta Boxed Warnings
Not Applicable
Vyzulta Warnings/Precautions
Warnings/Precautions
Do not exceed recommended dose (may reduce efficacy). History of ocular inflammation: not recommended if active inflammation. Aphakia. Pseudophakia with torn posterior lens capsule. Risk of macular edema. Bacterial keratitis may occur (due to multiple-dose containers). Contact lenses (remove; may reinsert lenses 15mins after administration). Pregnancy. Nursing mothers.
Vyzulta Pharmacokinetics
See Literature
Vyzulta Interactions
Interactions
Allow at least 5mins between application of other topical oph agents.
Vyzulta Adverse Reactions
Adverse Reactions
Conjunctival hyperemia, eye irritation, eye pain, instillation site pain; increased ocular pigmentation (eg, iris [may be permanent], eyelid, eyelashes), other eyelash/lid changes, macular edema (including cystoid macular edema).
Vyzulta Clinical Trials
See Literature
Vyzulta Note
Not Applicable
Vyzulta Patient Counseling
See Literature