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Pred-g Oph Oint Generic Name & Formulations
Legal Class
Rx
General Description
Prednisolone acetate 0.6%, gentamicin (as sulfate) 0.3%.
Pharmacological Class
Steroid + aminoglycoside.
See Also
How Supplied
Susp—5mL, 10mL; Oint—3.5g
Manufacturer
Mechanism of Action
Corticosteroids suppress the inflammatory response to a variety of agents and they probably delay or slow healing. Since corticosteroids may inhibit the body’s defense mechanism against infection, a concomitant antimicrobial drug may be used when this inhibition is considered to be clinically significant in a particular case.
Pred-g Oph Oint Indications
Indications
Ocular inflammation associated with infection.
Pred-g Oph Oint Dosage and Administration
Adult
½ inch 1–3 times daily; max 8g for initial ℞.
Children
Not established.
Pred-g Oph Oint Contraindications
Contraindications
Fungal, viral or mycobacterial infections.
Pred-g Oph Oint Boxed Warnings
Not Applicable
Pred-g Oph Oint Warnings/Precautions
Warnings/Precautions
Not for uncomplicated removal of foreign body. Corneal or scleral thinning. Glaucoma. Monitor for secondary infections, cataracts, and intraocular pressure in prolonged use. May mask signs of infection. Avoid abrupt cessation. Pregnancy. Nursing mothers: not recommended.
Pred-g Oph Oint Pharmacokinetics
Elimination
Renal. Half-life: 2.1–3.5 hours (prednisolone).
Pred-g Oph Oint Interactions
Not Applicable
Pred-g Oph Oint Adverse Reactions
Adverse Reactions
In prolonged use increased intraocular pressure, cataracts, corneal perforation, optic nerve damage, secondary infections. Ocular discomfort (eg, burning, stinging, hyperemia, pain, discharge, edema, irritation), visual impairment, blurry vision, foreign body sensation in eyes, dysgeusia, punctate keratitis, delayed wound healing, hypersensitivity or allergic skin reactions.
Pred-g Oph Oint Clinical Trials
See Literature
Pred-g Oph Oint Note
Not Applicable
Pred-g Oph Oint Patient Counseling
See Literature
