Polymyxin B/neomycin/hydrocortisone Oph Susp

— THERAPEUTIC CATEGORIES —
  • Ocular allergy/inflammation

Polymyxin B/neomycin/hydrocortisone Oph Susp Generic Name & Formulations

General Description

Polymyxin B sulfate 10000 Units, neomycin 0.35% (as sulfate), hydrocortisone 1%; per mL; contains thimerosal.

Pharmacological Class

Antibiotics + steroid.

How Supplied

Contact supplier.

Polymyxin B/neomycin/hydrocortisone Oph Susp Indications

Indications

Ocular inflammation associated with infection.

Polymyxin B/neomycin/hydrocortisone Oph Susp Dosage and Administration

Adult

1–2 drops or small amount of oint every 3–4 hours (may use susp more often); max 20mL or 8g per therapeutic course.

Children

Not recommended.

Polymyxin B/neomycin/hydrocortisone Oph Susp Contraindications

Contraindications

Ocular fungal, viral or mycobacterial infections.

Polymyxin B/neomycin/hydrocortisone Oph Susp Boxed Warnings

Not Applicable

Polymyxin B/neomycin/hydrocortisone Oph Susp Warnings/Precautions

Warnings/Precautions

Corneal or scleral thinning. Glaucoma. Monitor IOP, for secondary infections, and avoid abrupt cessation in prolonged use. Pregnancy (Cat.C). Nursing mothers: not recommended.

Polymyxin B/neomycin/hydrocortisone Oph Susp Pharmacokinetics

See Literature

Polymyxin B/neomycin/hydrocortisone Oph Susp Interactions

Not Applicable

Polymyxin B/neomycin/hydrocortisone Oph Susp Adverse Reactions

Adverse Reactions

Local irritation, sensitization, masks infection, delays healing; in prolonged use: increased IOP, cataracts, corneal perforation, optic nerve damage.

Polymyxin B/neomycin/hydrocortisone Oph Susp Clinical Trials

See Literature

Polymyxin B/neomycin/hydrocortisone Oph Susp Note

Notes

Formerly known under the brand name Cortisporin.

Polymyxin B/neomycin/hydrocortisone Oph Susp Patient Counseling

See Literature