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Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Generic Name & Formulations
Legal Class
Rx
General Description
Polymyxin B sulfate 10000 Units, neomycin 0.35% (as sulfate), bacitracin zinc 400 Units, hydrocortisone 1%; per g.
Pharmacological Class
Antibiotics + steroid.
How Supplied
Contact supplier.
Manufacturer
Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Indications
Indications
Ocular inflammation associated with infection.
Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Dosage and Administration
Adult
1–2 drops or small amount of oint every 3–4 hours (may use susp more often); max 20mL or 8g per therapeutic course.
Children
Not recommended.
Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Contraindications
Contraindications
Ocular fungal, viral or mycobacterial infections.
Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Boxed Warnings
Not Applicable
Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Warnings/Precautions
Warnings/Precautions
Corneal or scleral thinning. Glaucoma. Monitor IOP, for secondary infections, and avoid abrupt cessation in prolonged use. Pregnancy (Cat.C). Nursing mothers: not recommended.
Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Pharmacokinetics
See Literature
Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Interactions
Not Applicable
Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Adverse Reactions
Adverse Reactions
Local irritation, sensitization, masks infection, delays healing; in prolonged use: increased IOP, cataracts, corneal perforation, optic nerve damage.
Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Clinical Trials
See Literature
Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Note
Notes
Formerly known under the brand name Cortisporin.
Polymyxin B/neomycin/bacitracin/hydrocortisone Oph Oint Patient Counseling
See Literature
