Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint

— THERAPEUTIC CATEGORIES —
  • Ocular allergy/inflammation

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Generic Name & Formulations

General Description

Neomycin (as sulfate) 3.5mg, polymyxin B sulfate 10000 Units, dexamethasone 0.1%; per g.

Pharmacological Class

Antibiotics + steroid.

How Supplied

Tube—3.5g

Manufacturer

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Indications

Indications

Ocular inflammation associated with infection.

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Dosage and Administration

Adult

Apply small amount into the conjunctival sac(s) up to 3–4 times daily; max 8g per therapeutic course.

Children

Not recommended.

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Contraindications

Contraindications

Ocular fungal, viral or mycobacterial infections.

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Boxed Warnings

Not Applicable

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Warnings/Precautions

Warnings/Precautions

Do not inject into the eye. Corneal or scleral thinning. Glaucoma. Monitor IOP, and for secondary infections in prolonged use. Discontinue if sensitization reaction occurs. Pregnancy (Cat.C). Nursing mothers: not recommended.

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Pharmacokinetics

See Literature

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Interactions

Not Applicable

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Adverse Reactions

Adverse Reactions

Local irritation, sensitization (itching, swelling, conjunctival erythema), masks infection, delays healing; in prolonged use: increased IOP, cataracts, corneal perforation, optic nerve damage.

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Clinical Trials

See Literature

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Note

Not Applicable

Neomycin/polymyxin B Sulfates/dexamethasone Oph Oint Patient Counseling

See Literature