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Naphazoline Hcl Generic Name & Formulations
Legal Class
Rx
General Description
Naphazoline HCl 1mg (0.1%); oph soln; contains benzalkonium chloride.
Pharmacological Class
Sympathomimetic (imidazoline derivative).
How Supplied
Soln—15mL
Manufacturer
Naphazoline Hcl Indications
Indications
For use as a topical ocular vasoconstrictor.
Naphazoline Hcl Dosage and Administration
Adults and Children
Instill 1 or 2 drops in the conjunctival sac(s) every 3–4hrs as needed.
Naphazoline Hcl Contraindications
Contraindications
Anatomically narrow angle or in narrow-angle glaucoma.
Naphazoline Hcl Boxed Warnings
Not Applicable
Naphazoline Hcl Warnings/Precautions
Warnings/Precautions
Hypertension. Cardiovascular abnormalities. Diabetes. Hyperthyroidism. Infection. Injury. Children (esp. infants): may result in CNS depression leading to coma and marked reduction in body temperature. Discontinue if no relief obtained within 48hrs of therapy, if irritation, blurring or redness persists or increases, or if symptoms of systemic absorption occur. Pregnancy (Cat.C). Nursing mothers.
Naphazoline Hcl Pharmacokinetics
See Literature
Naphazoline Hcl Interactions
Interactions
Concomitant maprotiline or tricyclic antidepressants may potentiate pressor effect. Severe hypertensive crisis possible with concomitant MAOIs.
Naphazoline Hcl Adverse Reactions
Adverse Reactions
Ocular (eg, mydriasis, increased redness, irritation, discomfort, blurring, punctate keratitis, lacrimation, increased intraocular pressure); systemic (eg, dizziness, headache, nausea, sweating, nervousness, drowsiness, weakness, hypertension, cardiac irregularities, hyperglycemia).
Naphazoline Hcl Clinical Trials
See Literature
Naphazoline Hcl Note
Not Applicable
Naphazoline Hcl Patient Counseling
See Literature
