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Iyuzeh Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Carton—30
Manufacturer
Generic Availability
NO
Mechanism of Action
Latanoprost is a prostaglandin F2α analogue that is believed to reduce the IOP by increasing the outflow of aqueous humor.
Iyuzeh Indications
Indications
Open-angle glaucoma. Ocular hypertension.
Iyuzeh Dosage and Administration
Adult
Instill 1 drop in the affected eye(s) once daily in the PM.
Children
Not established.
Iyuzeh Contraindications
Not Applicable
Iyuzeh Boxed Warnings
Not Applicable
Iyuzeh Warnings/Precautions
Warnings/Precautions
Do not exceed recommended dose (may reduce efficacy). Ocular inflammation. Aphakia. Pseudophakia with torn posterior lens capsule. Risk for macular edema. History of herpetic keratitis. Contact lenses (remove; may reinsert lenses 15mins after administration). Pregnancy. Nursing mothers.
Iyuzeh Pharmacokinetics
Absorption
Absorbed through the cornea where the isopropyl ester prodrug is hydrolyzed to the acid form to become biologically active.
Distribution
Volume of distribution: 0.16 ± 0.02 L/kg.
Elimination
Renal. Half-life: 17 minutes.
Iyuzeh Interactions
Interactions
Allow at least 5mins between application of other topical oph agents.
Iyuzeh Adverse Reactions
Adverse Reactions
Conjunctival hyperemia, eye irritation, eye pruritus, abnormal sensation in eye, foreign body sensation in eyes, vision blurred, increased lacrimation; increased ocular pigmentation (eg, iris, eyelid, eyelashes; may be permanent), other eyelash/lid changes.
Iyuzeh Clinical Trials
See Literature
Iyuzeh Note
Not Applicable
Iyuzeh Patient Counseling
See Literature
Images
