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Iopidine 1% Generic Name & Formulations
Legal Class
Rx
General Description
Apraclonidine (as HCl) 1%; oph soln; contains benzalkonium chloride.
Pharmacological Class
Alpha-2 agonist.
See Also
How Supplied
Soln 0.5%—contact supplier; 1% (0.1mL)—2
Manufacturer
Iopidine 1% Indications
Indications
To control or prevent post-surgical elevations in IOP after argon laser trabeculoplasty or iridotomy, or Nd:YAG posterior capsulotomy.
Iopidine 1% Dosage and Administration
Adult
Instill 1 drop into operative eye 1hr before laser surgery and a second drop immediately after procedure is completed.
Children
Not established.
Iopidine 1% Contraindications
Contraindications
Clonidine allergy. Concomitant MAOIs.
Iopidine 1% Boxed Warnings
Not Applicable
Iopidine 1% Warnings/Precautions
Warnings/Precautions
Monitor visual fields. Severe uncontrolled cardiovascular disease, hypertension, coronary insufficiency. Recent myocardial infarction. Cerebrovascular disease. Raynaud's disease. Thromboangiitis obliterans. History of vasovagal attack. Discontinue if ocular allergic-like reactions occur. Renal or hepatic impairment: closely monitor cardiovascular parameters. Depression. May mask hypoglycemia. Pregnancy. Nursing mothers (1% soln: discontinue nursing temporarily for 1 day of use).
Iopidine 1% Pharmacokinetics
See Literature
Iopidine 1% Interactions
Interactions
See Contraindications. May potentiate CNS depressants (eg, alcohol, barbiturates, opiates, sedatives, anesthetics). Caution with TCAs, β-blockers, antihypertensives, cardiac glycosides, others (eg, clonidine). Concomitant CV drugs: monitor HR, BP periodically.
Iopidine 1% Adverse Reactions
Adverse Reactions
Hyperemia, pruritus, dry mouth, itching, discomfort, tearing, dizziness, solmnolence, lid edema, blurred vision, foreign body sensation, dry eye, conjunctivitis, discharge, blanching; tachyphylaxis may develop after 1 month; also in post-laser surgery: upper lid elevation, inflammation, nasal decongestion, mydriasis, irregular HR.
Iopidine 1% Clinical Trials
See Literature
Iopidine 1% Note
Not Applicable
Iopidine 1% Patient Counseling
See Literature
