Eysuvis

Delayed Healing and Corneal Perforation

• Corticosteroids may delay healing and cause corneal and scleral thinning.
• Use of topical corticosteroids in the presence of corneal or scleral thinning may lead to perforation.
• Initial prescription and each renewal of medication should be made after examination of the patient with the aid of magnification, and, where appropriate, fluorescein staining.

Intraocular Pressure (IOP) Increase

• Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, as well as defects in visual acuity and fields of vision.
• Use with caution in the presence of glaucoma.
• Renewal of medication should be made only after examination of the patient and evaluation of IOP.

Cataracts

• Use of corticosteroids may result in posterior subcapsular cataract formation.

Bacterial Infections

• Risk of secondary ocular infections increased as corticosteroids suppress the host response.
• Corticosteroids may mask infection or enhance existing infection in acute purulent conditions of the eye.

Viral Infections

• History of herpes simplex: use caution.
• Use of ocular corticosteroids may prolong the course and may exacerbate the severity of many viral infections of the eye (including herpes simplex).

Fungal Infections

• Long-term local corticosteroid application: fungal infections of the cornea may develop.
• Consider fungus invasion in any persistent corneal ulceration where a corticosteroid has been used or is in use.
• Fungal cultures should be taken when appropriate.

Risk of Contamination

• Do not allow the dropper tip to touch any surface, as this may contaminate the suspension.

Contact Lens Wear

• The preservative in Eysuvis may be absorbed by soft contact lenses. 
• Contact lenses should be removed prior to instillation and may be reinserted 15 minutes following administration.