Dexamethasone Sodium Phosphate Ophthalmic Solution

— THERAPEUTIC CATEGORIES —
  • Ocular allergy/inflammation

Dexamethasone Sodium Phosphate Ophthalmic Solution Generic Name & Formulations

General Description

Dexamethasone sodium phosphate 0.1%; oph soln; contains benzalkonium chloride.

Pharmacological Class

Steroid.

How Supplied

Soln—5mL

Manufacturer

Dexamethasone Sodium Phosphate Ophthalmic Solution Indications

Indications

Steroid responsive inflammatory conditions of the eye.

Dexamethasone Sodium Phosphate Ophthalmic Solution Dosage and Administration

Adult

Initial therapy: 1 or 2 drops in conjunctival sac every hour during the day and every two hours during the night. When favorable response observed, reduce dose to 1 drop every 4 hours; may reduce later to 1 drop 3 or 4 times daily.

Children

Not established.

Dexamethasone Sodium Phosphate Ophthalmic Solution Contraindications

Contraindications

Epithelial herpes simplex keratitis. Acute infectious stages of vaccinia, varicella, and many other diseases of the cornea and conjunctiva. Mycobacterial infection of the eye. Fungal diseases of ocular or auricular structures. Perforation of a drum membrane.

Dexamethasone Sodium Phosphate Ophthalmic Solution Boxed Warnings

Not Applicable

Dexamethasone Sodium Phosphate Ophthalmic Solution Warnings/Precautions

Warnings/Precautions

Monitor intraocular pressure if used for >10 days. Wait at least 15 minutes before inserting contact lenses. Pregnancy (Cat.C). Nursing mothers: not recommended.

Dexamethasone Sodium Phosphate Ophthalmic Solution Pharmacokinetics

See Literature

Dexamethasone Sodium Phosphate Ophthalmic Solution Interactions

Not Applicable

Dexamethasone Sodium Phosphate Ophthalmic Solution Adverse Reactions

Adverse Reactions

Glaucoma with optic nerve damage, visual acuity and field defects, posterior subcapsular cataract formation, secondary ocular infection from pathogens including herpes simplex, perforation of the globe; rare: stinging, burning, filtering blebs following cataract surgery.

Dexamethasone Sodium Phosphate Ophthalmic Solution Clinical Trials

See Literature

Dexamethasone Sodium Phosphate Ophthalmic Solution Note

Not Applicable

Dexamethasone Sodium Phosphate Ophthalmic Solution Patient Counseling

See Literature