Bromfenac

— THERAPEUTIC CATEGORIES —
  • Ocular allergy/inflammation

Bromfenac Generic Name & Formulations

General Description

Bromfenac 0.09%, oph soln; contains benzalkonium chloride, sulfites.

Pharmacological Class

NSAID.

How Supplied

Contact supplier.

Bromfenac Indications

Indications

Post-operative inflammation and reduction of ocular pain following cataract extraction.

Bromfenac Dosage and Administration

Adult

≥18yrs: 1 drop in affected eye(s) once daily starting 1 day before surgery, continued on day of surgery, and for 14 days post-op. May be given with other topical ophthalmics (eg, alpha-agonists, beta-blockers, carbonic anhydrase inhibitors, cycloplegics, mydriatics); administer at least 5 minutes apart.

Children

<18yrs: not recommended.

Bromfenac Contraindications

Not Applicable

Bromfenac Boxed Warnings

Not Applicable

Bromfenac Warnings/Precautions

Warnings/Precautions

Bleeding tendencies. May slow or delay wound healing. Complicated/repeat ocular surgeries. Corneal defects/denervation. Ocular surface diseases. Rheumatoid arthritis. Diabetes. Monitor cornea; discontinue if corneal epithelial breakdown occurs. Risk of corneal adverse events may be increased if used >24hrs before surgery, or beyond 14-days post-op. Contact lenses (remove during therapy). Pregnancy (Cat.C; avoid during late pregnancy). Nursing mothers.

Bromfenac Pharmacokinetics

See Literature

Bromfenac Interactions

Interactions

Concomitant topical corticosteroids may potentiate healing problems. Caution with concomitant drugs that prolong bleeding time.

Bromfenac Adverse Reactions

Adverse Reactions

Ocular effects (eg, abnormal sensation, conjunctival hyperemia, burning, stinging, pain, pruritus, redness, iritis), headache; keratitis, corneal reactions (eg, epithelial breakdown, thinning, erosion, ulceration/perforation).

Bromfenac Clinical Trials

See Literature

Bromfenac Note

Notes

Formerly known under the brand name Bromday.

Bromfenac Patient Counseling

See Literature