Betaxolol Hcl Ophthalmic Solution

— THERAPEUTIC CATEGORIES —
  • Glaucoma

Betaxolol Hcl Ophthalmic Solution Generic Name & Formulations

General Description

Betaxolol HCl 0.5%; oph soln; contains benzalkonium chloride.

Pharmacological Class

Cardioselective beta-blocker.

How Supplied

Soln—5mL, 10mL, 15mL

Manufacturer

Betaxolol Hcl Ophthalmic Solution Indications

Indications

Open-angle glaucoma. Ocular hypertension.

Betaxolol Hcl Ophthalmic Solution Dosage and Administration

Adult

1–2 drops in affected eye(s) twice daily. Concomitant therapy with pilocarpine and other miotics, and/or epinephrine and/or carbonic anhydrase inhibitors can be instituted if needed.

Children

Not established.

Betaxolol Hcl Ophthalmic Solution Contraindications

Contraindications

Sinus bradycardia. Greater than 1st-degree AV block. Cardiogenic shock. Overt cardiac failure.

Betaxolol Hcl Ophthalmic Solution Boxed Warnings

Not Applicable

Betaxolol Hcl Ophthalmic Solution Warnings/Precautions

Warnings/Precautions

History of cardiac failure or heart block. Discontinue at 1st sign of cardiac failure. Asthma. Pulmonary impairment. Diabetes (esp. labile). May mask hypoglycemia and hyperthyroidism. May potentiate muscle weakness. Discontinue before general anesthesia. Avoid abrupt cessation. Pregnancy (Cat.C). Nursing mothers.

Betaxolol Hcl Ophthalmic Solution Pharmacokinetics

See Literature

Betaxolol Hcl Ophthalmic Solution Interactions

Interactions

May potentiate or be potentiated by systemic β-blockers. May potentiate reserpine, hypoglycemics. May antagonize adrenergic psychotropics.

Betaxolol Hcl Ophthalmic Solution Adverse Reactions

Adverse Reactions

Transient discomfort, tearing. Rarely: decreased corneal sensitivity, erythema, itch, corneal punctate staining, keratitis, anisocoria, photophobia, depression, headache, bradycardia, dyspnea, hives.

Betaxolol Hcl Ophthalmic Solution Clinical Trials

See Literature

Betaxolol Hcl Ophthalmic Solution Note

Notes

Formerly known under the brand name Betoptic.

Betaxolol Hcl Ophthalmic Solution Patient Counseling

See Literature